Skip to main content
Log in

Salivary duct carcinoma: report of a case and review of the literature

  • Case Report
  • Published:
Virchows Archiv A Aims and scope Submit manuscript

Summary

Salivary duct carcinoma is a rare primary tumour of the salivary glands arising most frequently in the parotid gland. It has a male preponderance and occurs most often in patients over the age of 50 years. Its distinctive histological features include dilated ducts containing cells arranged in cribriform, papillary or solid patterns often with central necrosis and reminiscent of intraduct carcinoma of the breast. These features are associated with an obvious invasive component. It is an aggressive neoplasm and may metastasize widely, causing death in a high proportion of cases.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Afzelius LE, Cameron WR, Svensson C (1987) Salivary duct carcinoma — a clinicopathologic study of 12 cases. Head Neck Surg 9:151–156

    Google Scholar 

  • Azzopardi JG (1979) Problems in breast pathology. Major problems in pathology vol 11. Saunders, Philadelphia, pp 131–133

    Google Scholar 

  • Batsakis JG (1980) Salivary gland neoplasia: an outcome of modified morphogenesis and cyto-differentiation. Oral Surg 49:229–232

    Google Scholar 

  • Batsakis JG, Regezi JA, Luna MA, El Naggar A (1989) Histogenesis of salivary gland neoplasms: a postulate with prognostic implications. J Laryngol Otol 103:939–944

    Google Scholar 

  • Brandwein MS, Jagirdar J, Patil J, Biller H, Kaneko M (1990) Salivary duct carcinoma (cribriform salivary carcinoma of excretory ducts). A clinicopathologic and immunohistochemical study of twelve cases. Cancer 65:2307–2314

    Google Scholar 

  • Chen KTK (1983) Intraduct carcinoma of the minor salivary gland. J Laryngol Otol 97:189–191

    Google Scholar 

  • Chen KTK, Hafez GR (1981) Infiltrating salivary duct carcinoma. A clinicopathological study of five cases. Arch Otolaryngol 107:37–39

    Google Scholar 

  • Corio RL, Sciubba JJ, Brannon RB, Batsakis JG (1982) Epithelialmyoepithelial carcinoma of intercalated duct origin; a clinicopathologic and ultrastructural assessment of sixteen cases. Oral Surg 53:280–287

    Google Scholar 

  • Evans RW, Cruickshank AH (1970) Epithelial tumours of the salivary glands. Major problems in pathology, vol 1. Saunders, Philadelphia, pp 265–275

    Google Scholar 

  • Eveson JW, Cawson RA (1985) Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol 146:51–58

    Google Scholar 

  • Fayemi AO, Toker C (1974) Salivary duct carcinoma. Arch Otolaryngol 99:366–368

    Google Scholar 

  • Ferlito A, Gale N, Hvala H (1981) Laryngeal salivary duct carcinoma. A light and electron microscopic study. J Laryngol Otol 95:731–738

    Google Scholar 

  • Gal R, Strauss M, Zohar Y, Kessler E (1985) Salivary duct carcinoma of the parotid gland. Cytologic and histopathologic study. Acta Cytol 29:454–456

    Google Scholar 

  • Garland TA, Innes DJ, Fechner RE (1984) Salivary duct carcinoma: an analysis of four cases with review of the literature. Am J Clin Pathol 81:436–441

    Google Scholar 

  • Hui KK, Batsakis JG, Luna MM, Mackay B, Byers RM (1986) Salivary duct adenocarcinoma: a high grade malignancy. J Laryngol Otol 100:105–114

    Google Scholar 

  • Innes DJ, Garland TA, Fechner RE (1982) Structures in salivary gland intraductal adenocarcinoma. Ultrastruct Pathol 3:193–197

    Google Scholar 

  • Kahn HG, Baumal R, Marks A, Dardick I, Nostrand AWP van (1985) Myoepithelial cells in salivary gland tumours. An immunohistochemical study. Arch Pathol Lab Med 109:190–195

    Google Scholar 

  • Kleinsasser O, Klein HJ, Hubner G (1968) Speichelgangcarcinome: Ein den Milchgangcarcinomen der Brustdrüse analoge Gruppe von Speicheldrüsentumoren. Arch Klin Exp Ohren-Nasen-Kehlkopfheilkd 192: 100–115

    Google Scholar 

  • Lopez JI, Nevado M, Eizaguirre B (1990) Salivary duct adenocarcinoma (letter). J Clin Pathol 43:608

    Google Scholar 

  • Luna MA, Batsakis JG, Ordonez NG, Mackay B, Tortoledo ME (1987) Salivary gland adenocarcinomas. Clinicopathologic analysis of three distinctive types. Semin Diagn Pathol 4:117–135

    Google Scholar 

  • Pesce C, Colacino R, Buffa P (1986) Duct carcinoma of the minor salivary glands. A case report. J Laryngol Otol 100:611–613

    Google Scholar 

  • Thackray AC, Lucas RB (1974) Tumors of the major salivary glands. Atlas of tumor pathology, 2nd series, fascicle 10. Armed Forces Institute of Pathology, Washington, D.C., pp 102

    Google Scholar 

  • Zohar Y, Shem-Tov Y, Gal R (1988) Salivary duct carcinoma in major and minor salivary glands. A clinicopathological analysis of four cases. J Craniomaxillofac Surg 16:320–323

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Butterworth, D.M., Jones, A.W. & Kotecha, B. Salivary duct carcinoma: report of a case and review of the literature. Vichows Archiv A Pathol Anat 420, 371–374 (1992). https://doi.org/10.1007/BF01600218

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01600218

Key words

Navigation