Abstract
A total of 5,366 pregnant Turkish women were screened for hepatitis B surface antigen (HBsAg) and 225 (4.2%) of them were found to be positive. Hepatitis B e antigen (HBeAg) was detected in 6.2% of HBsAg-positive pregnant women. The overall prevalence of HBsAg and antibody to HBsAg (anti-HBs) among the spouses, previous children, mothers and first degree relatives of the HBsAg-positive pregnant women was 56%, 49%, 79% and 74% respectively. The prevalence of HBsAg is thus high in pregnant Turkish women with familial clustering of hepatitis B virus infection.
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Lo KJ, Tsai YT, Lee SD, Yeh CL, Wang JY, Chiang BN, Wu TC, Yeh PSH, Goudeau A, Cousaget P, Tong MJ: Combined passive and active immunization for interruption of perinatal transmission of HBV in Taiwan. Hepatogastroenterology 1985, 321: 65–68.
Maynard JE, Kane M, Alter MJ, Hadler SC: Control of hepatitis B by immunization: global perspectives. In: Zuckerman AJ (ed): Viral hepatitis B and liver diseases. Alan R. Liss, New York, 1988, p. 967–969.
Davis LG, Weber DJ, Lemon SM: Horizontal transmission of hepatitis B virus. Lancet 1989, ii: 889–893.
Okada K, Kamiyama I, Inomata M, Imai M, Miyakawa Y, Mayumi M: e antigen and anti-e in the serum of asymptomatic carrier mothers as indicators of perinatal transmission of hepatitis B virus to their infants. New England Journal of Medicine 1976, 294: 746–749.
Schaefer E, Koeppen H, Wirth S: Low level virus replication in infants with vertically transmitted fulminant hepatitis and their anti-HBe positive mothers. European Journal of Pediatrics 1993, 152: 581–584.
Yotsumoto S, Kojima M, Shoji I, Yamamoto K, Okamoto H, Mishiro S: Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses. Hepatology 1992, 16: 31–35.
Beath SV, Boxall EH, Watson RM, Tarlow MJ, Kelly DA: Fulminant hepatitis B in infants born to anti-HBe hepatitis carrier mothers. British Medical Journal 1992, 304: 1169–1170.
Kilicturgay K: Viral hepatitis in Turkey. In: Kilicturgay K (ed): Viral hepatitis '92. Nobel Tip Kitapevi, Istanbul, 1992, p. 1–15.
Cakaloglu Y, Okten A, Yalcin S: Seroepidemiology of hepatitis B virus infection in Turkey. Turkish Journal of Gastroenterohepatology 1990, 1: 49–53.
Balistreri WF: Viral hepatitis. Pediatric Clinics of North America 1988, 35: 375–407.
Robinson WS: Hepatitis B virus and hepatitis delta virus. In: Mandell GL, Douglas RG, Bennett JE(ed): Principles and practice of infectious diseases. Churchill Livingstone, New York, 1990, p. 1204–1224.
Bernier RH, Sampliner R, Gerety R: Hepatitis B infection in households of chronic carriers of hepatitis B surface antigen. American Journal of Epidemiology 1982, 116: 199–211.
Toukan AU, Sharaiha ZK, Abu-El-Rub OM: The epidemiology of hepatitis B virus among family members in the Middle East. American Journal of Epidemiology 1990, 132: 220–232.
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Kuru, U., Turan, O., Kuru, N. et al. Prevalence of hepatitis B virus infection in pregnant Turkish women and their families. Eur. J. Clin. Microbiol. Infect. Dis. 15, 248–251 (1996). https://doi.org/10.1007/BF01591364
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DOI: https://doi.org/10.1007/BF01591364