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Isolation of “Helicobacter heilmannii” from human tissue

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References

  1. Hanninen ML, Jalava K, Saari S, Happonen J, Westermarck E: Culture of “Gastrospirillum” from gastric biopsies of dogs. European Journal of Clinical Microbiology & Infectious Diseases 1995, 14: 145–146.

    Google Scholar 

  2. Goodwin CS, Armstrong JA, Chilvers T, Peters M, Collins MD, Sly L, McConnell W, Harper WE: Transfer ofCampylobacter pylori andCampylobacter mustelae toHelicobacter pylori gen. nov. andHelicobacter mustelae comb. nov.) respectively. International Journal of Systematic Bacteriology 1989, 39: 397–405.

    Google Scholar 

  3. World Health Organisation: IARC monographs on the evaluation of carcinogenic risks to humans. World Health Organization, Geneva, 1994, vol. 61, p. 177–240.

    Google Scholar 

  4. Coghlan A: Big bucks buy up genome secrets. New Scientist 1995, September 30: 4.

    Google Scholar 

  5. Lee A, Hazell SL, O'Rourke J, Kouprach S: Isolation of a spiral-shaped bacterium from the cat stomach. Infection and Immunity 1988, 56: 2843–2850.

    Google Scholar 

  6. Paster BJ, Lee A, Fox JG, Dewhirst FE, Tordoff LA, Fraser GJ, O'Rourke J, Taylor NS, Ferrero R: Phytogeny ofHelicobacter felis sp. nov.,Helicobacter mustelae, and related bacteria. International Journal of Systematic Bacteriology 1991, 41: 31–38.

    Google Scholar 

  7. Dick E, Lee A, Watson G, O'Rourke J: Use of the mouse for the isolation and investigation of stomach-associated, spiral-helical shaped bacteria from man and other animals. Journal of Medical Microbiology 1989, 29: 55–62.

    Google Scholar 

  8. Mellgard B, Arvidsson S, Lee A, Sundell G, Larsson H: TheH. felis-infected rat as a model for humanH. pylori infection — colonisation pattern and inflammatory response. American Journal of Gastroenterology 1994, 89: 1320.

    Google Scholar 

  9. Dick-Hegedus E, Lee A: Use of a mouse model to examine anti-Helicobacter pylori agents. Scandinavian Journal of Gastroenterology 1991, 26: 909–915.

    Google Scholar 

  10. Enno A, O'Rourke J, Howlett CR, Jack A, Dixon MF, Lee A: MALToma-like lesions in the murine gastric mucosa following long term infection withHelicobacter felis: a mouse model ofHelicobacter pylori induced gastric lymphoma. American Journal of Pathology 1995, 147: 217–222.

    Google Scholar 

  11. Chen M, Lee A, Hazell SL: Immunisation againstHelicobacter infection in a mouse/Helicobacter felis model. Lancet 1992, 339: 1120–1121.

    Google Scholar 

  12. Chen MH, Lee A, Hazell S, Hu PJ, Li YY: Immunisation against gastric infection withHelicobacter species —first step in the prophylaxis of gastric cancer? International Journal of Medical Microbiology 1993, 280: 155–165.

    Google Scholar 

  13. Buck F, Doidge C, Lee A, Manne U, Gust I: Effective protection againstHelicobacter felis infection in mice withH. pylori antigens. American Journal of Gastroenterology 1994, 89: 1335.

    Google Scholar 

  14. Czinn SJ, Cai A, Nedrud JG: Protection of germ-free mice from infection byHelicobacter felis after active oral or passive IgA immunization. Vaccine 1993, 11: 637–642.

    Google Scholar 

  15. Michetti P, Corthesy-Theulaz I, Davin C, Haas R, Vaney AC, Heitz M, Bille J, Kraehenbuhl JP, Saraga E, Blum AC: Immunisation of BALB/c mice againstHelicobacter felis infection withH. pylori urease. Gastroenterology 1994, 107: 1002–1011.

    Google Scholar 

  16. Thomas WD, Lee CK, Lofsky A, Nichols R, Houle D: Effect of oral immunization withHelicobacter pylori antigens on colonisation byH. felis in mice. Acta Gastro-Enterologica Belgica 1993, 56, Supplement: 54.

    Google Scholar 

  17. Lee A, Chen MH: Successful immunization against gastric infection withHelicobacter species: use of a cholera toxin B-subunit-whole-cell vaccine. Infection and Immunity 1994, 62: 3594–3597.

    Google Scholar 

  18. Dent JC, McNulty CAM, Uff JC, Wilkinson SP, Gear MWL: Spiral organisms in the gastric antrum. Lancet 1987, ii: 96.

    Google Scholar 

  19. Logan RP, Karim QN, Poison RJ, Walker MM, Baron JH: “Gastrospirillum hominis” infection of the stomach. Lancet 1989, ii: 672.

    Google Scholar 

  20. Lord MG, Taylor CJ, Nour S: “Gastrospirillum hominis” infection of the stomach. Lancet 1989, ii: 672.

    Google Scholar 

  21. McNulty CAM, Dent JC, Curry A, Uff JS, Ford GA, Gear MW, Wilkinson SP: New spiral bacterium in gastric mucosa. Journal of Clinical Pathology 1989, 42: 585–591.

    Google Scholar 

  22. Lee A, Eckstein RP, Fevre DI, Dick E, Kellow JE: NonCampylobacter pylori spiral organisms in the gastric antrum. Australian and New Zealand Journal of Medicine 1989, 19: 156–158.

    Google Scholar 

  23. Lee A, Dent J, Hazell S, McNulty C: Origin of spiral organisms in human gastric antrum. Lancet 1988, i: 300–301.

    Google Scholar 

  24. Fischer R, Samisch W, Schwenke E: “Gastrospirillum hominis”: another four cases. Lancet 1990, 335: 59.

    Google Scholar 

  25. Flejou JF, Diomande I, Molas G, Goldfain D, Rotenberg A, Florent M, Potet F: Human chronic gastritis associated with non-Helicobacterpylori spiral organisms (Gastrospirillum hominis). Four cases and review of the literature. Gastroenterologie Clinique et Biologique 1990, 14: 806–810.

    Google Scholar 

  26. Cayla R, Vialette G, Seurat PL, MacGrogan G, Rudel A, Sauvet P, Hervouet M: Role of non-Helicobacter pylori spiral organisms (Gastrospirillum hominis) in the human stomach. Italian Journal of Gastroenterology 1991, 23, Supplement 2: 72.

    Google Scholar 

  27. Logan RP, Polson RJ, Baron JH, Walker MM: New spiral bacterium in the gastric mucosa:Gastrospirillum hominis. Journal of Clinical Pathology 1990, 43: 262–263.

    Google Scholar 

  28. Queiroz DM, Cabral MM, Nogueira AM, Barbosa AJ, Rocha GA, Mendes EN: Mixed gastric infection by “Gastrospirillum hominis” andHelicobacter pylori. Lancet 1990, ii: 507–508.

    Google Scholar 

  29. Wegmann W, Aschwanden M, Schaub N, Aenishanslin W, Gyr K: Gastritis associated withGastrospirillum hominis — a zoonosis? Schweizer Medizinische Wochenschrift 1991, 21: 245–254.

    Google Scholar 

  30. Zhou DY, Yang HT, Zhang WD: Gastritis due to “Gastrospirillum hominis.” Italian Journal of Gastroenterology 1991, 23, Supplement 2: 83.

    Google Scholar 

  31. Kubonova K, Trupl J, Jancula L, Polak E, Viablik V: Presence of spiral bacteria (“Gastrospirillum hominis”) in the gastric mucosa. European Journal of Clinical Microbiology & Infectious Diseases 1991, 10: 459–460.

    Google Scholar 

  32. Ierardi E, Monno R, Mongelli A, Allegretta L, Milone E, Rizzi S, Panza P, Coppolecchia P, Francavilla A:Gastrospirillum hominis associated with chronic active gastritis: the first report from Italy. Italian Journal of Gastroenterology 1991, 23: 86–87.

    Google Scholar 

  33. Oliva MM, Lazenby AJ, Perman LA: Gastritis associated withGastrospirillum hominis in children — comparison withhelicobacter pylori and review of the literature. Modern Pathology 1993, 6: 513–515.

    Google Scholar 

  34. Mazzucchelli L, Wildersmith CH, Ruchti C, Meyerwyss B, Merki HS:Gastrospirillum hominis in asymptomatic, healthy individuals. Digestive Disease and Science 1993, 38: 2087–2089.

    Google Scholar 

  35. Debongnie JC, Donnay M, Mairesse J, Lamy V, Dekoninck X, Ramdani B: Acute gastric ulcerations andGastrospirillum hominis. Another cause of gastric ulcer? Acta Gastro-Enterologica Belgica 1993, 56, Supplement: 56.

    Google Scholar 

  36. Lavelle J, Conklin F, Mitros S, Landas S: Transmission of “Gastrospirillum hominis” from cat to man. Gastroenterology 1992, 104: A.

    Google Scholar 

  37. Thomson MA, Storey P, Greer R, Cleghorn GJ: Caninehuman transmission ofGastrospirillum hominis. Lancet 1994, 343: 1605–1607.

    Google Scholar 

  38. Curry A: Canine-to-human transmission ofGastrospirillum hominis. Lancet 1994, 344: 190.

    Google Scholar 

  39. Debongnie JC:Gastrospirillum hominis prevalence. Digestive Disease and Science 1994, 39: 1618.

    Google Scholar 

  40. Stolte M, Wellens E, Bethke B, Ritter M, Eidt H:Helicobacter heilmannii (formerlyGastrospirillum hominis) gastritis: an infection transmitted by animals? Scandinavian Journal of Gastroenterology 1994, 29: 1061–1064.

    Google Scholar 

  41. Heilmann KL, Borchard F: Further observations on human spirobacteria. In: Menge H, Gregor M, Tytgat GNJ, Marshall BJ, McNulty CAM (ed):Helicobacter pylori 1990. Springer-Verlag, Berlin, 1991, p. 63–70.

    Google Scholar 

  42. Heilmann KL, Borchard F: Gastritis due to spiral shaped bacteria other thanHelicobacter pylori: clinical, histological, and ultrastructural findings. Gut 1991, 32: 137–140.

    Google Scholar 

  43. Webb PM, Knight T, Greaves S, Wilson A, Newell DG, Elder J, Forman D: Relation between infection withHelicobacter pylori and living conditions in childhood — evidence for person to person transmission in early life. British Medical Journal 1994, 308: 750–753.

    Google Scholar 

  44. Vincent P, Gottrand F, Pernes P, Husson MO, Lecomtehoucke M, Turck D, Leclerc H: High prevalence ofHelicobacter pylori infection in cohabiting children — epidemiology of a cluster, with special emphasis on molecular typing. Gut 1994, 35: 313–316.

    Google Scholar 

  45. Mitchell HM, Bohane T, Hawkes RA, Lee A:Helicobacter pylori infection within families. International Journal of Medical Microbiology 1993, 280: 128–136.

    Google Scholar 

  46. Mitchell HM, Li YY, Hu PJ, Liu Q, Chen M, Du GG, Wang ZJ, Lee A, Hazell SL: Epidemiology ofHelicobacter pylori in Southern China — identification of early childhood as the critical period for acquisition. Journal of Infectious Diseases 1992, 166: 149–153.

    Google Scholar 

  47. Hazell SL, Mitchell HM, Hedges M, Shi X, Hu PJ, Li YY, Lee A, Reiss-Levy E: Hepatitis A and evidence against the community dissemination ofHelicobacter pylori via feces. Journal of Infectious Diseases 1994, 170: 686–689.

    Google Scholar 

  48. Vincent P: Transmission and acquisition ofHelicobacter pylori infection: evidences and hypothesis. Biomedical Pharmacotherapy 1995, 49: 11–18.

    Google Scholar 

  49. Mitchell HM, Hazell SL, Hedges M, Li YY, Lee A, Shi X, Hu PJ, Reiss-Levy E: Evidence against community wide fecal-oral transmission ofHelicobacter pylori. American Journal of Gastroenterology 1989, 89: 1309.

    Google Scholar 

  50. Banatvala N, Mayo K, Megraud F, Jennings R, Deeks JJ, Feldman RA: The cohort effect andHelicobacter pylori. Journal of Infectious Diseases 1993, 168: 219–221.

    Google Scholar 

  51. Otto G, Hazell SL, Fox JG, Howlett CR, Murphy JC, O'Rourke JL, Lee A: Animal and public health implications of gastric colonization of cats by helicobacter-like organisms. Journal of Clinical Microbiology 1994, 32: 1043–1049.

    Google Scholar 

  52. Lee A, Eckstein RP, Fevre DI, Dick E, Kellow JE: NonCampylobacter pylori spiral organisms in the gastric antrum. Australian and New Zealand Journal of Medicine 1989, 19: 156–158.

    Google Scholar 

  53. Dick E, Lee A, Watson G, O'Rourke J: Use of the mouse for the isolation and investigation of stomach-associated spiral shaped bacteria from man and other animals. Journal of Medical Microbiology 1989, 29: 55–62.

    Google Scholar 

  54. Solnick JV, O'Rourke J, Lee A, Paster BJ, Dewhirst FE, Tompkins LS: An uncultured gastric spiral organism is a newly identified helicobacter in humans. Journal of Infectious Diseases 1993, 168: 379–385.

    Google Scholar 

  55. O'Rourke JL, Solnick J, Lee A, Tompkins LS: “Helicobacter heilmannii” (previouslyGastrospirillum), a new species ofHelicobacter in humans and animals. Irish Journal of Medical Science 1992, 161, Supplement 10: 31.

    Google Scholar 

  56. Solnick JV, O'Rourke J, Lee A, Tompkins LS: Molecular analysis of urease genes from a newly identified uncultured species of helicobacter. Infection and Immunity 1994, 62: 1631–1638.

    Google Scholar 

  57. Sidebotham RL, Baron JH: Hypothesis:Helicobacter pylori, urease, mucus, and gastric ulcer. Lancet 1990, i: 193–195.

    Google Scholar 

  58. Ferrero RL, Hazell SL, Lee A: The urease enzymes ofCampylobacter pylori and a related bacterium. Journal of Medical Microbiology 1988, 27: 33–40.

    Google Scholar 

  59. McColm AA, Bagshaw J, O'Malley CO, McLaren A: Is urease a lethal target for therapy ofHelicobacter pylori? Microbial Ecology in Health and Disease 1991, 4, Supplement: 145.

    Google Scholar 

  60. Danon SJ, O'Rourke JL, Moss ND, Lee A: The importance of local acid production in the distribution ofHelicobacter felis in the mouse stomach. Gastroenterology 1995, 108: 1386–1395.

    Google Scholar 

  61. Phillips MW, Lee A: Isolation and characterization of a spiral bacterium from the crypts of rodent gastrointestinal tracts. Applied and Environmental Microbiology 1983, 45: 675–683.

    Google Scholar 

  62. Lee A, Phillips MW, O'Rourke JL, Paster BJ, Dewhirst FE, Fraser GJ, Fox JG, Sly LI, Romaniuk PJ, Trust TJ, Kouprach S:Helicobacter muridarum sp. nov., a microaerophilic helical bacterium with a novel ultrastructure isolated from the intestinal mucosa of rodents. International Journal of Systematic Bacteriology 1992, 42: 27–36.

    Google Scholar 

  63. Eaton KA, Krakowka S: Effect of gastric pH on ureasedependent colonization of gnotobiotic piglets byHelicobacter pylori. Infection and Immunity 1994, 62: 3604–3607.

    Google Scholar 

  64. Mendz GL, Hazell SL: Aminoacid utilization byHelicobacter pylori. American Journal of Gastroenterology 1994, 89: 1289.

    Google Scholar 

  65. Mendz GL, Hazell SL: Fumarate catabolism inHelicobacter pylori. Biochemistry and Molecular Biology International 1993, 31: 325–332.

    Google Scholar 

  66. Hazell SL, Mendz GL: The metabolism and enzymes ofHelicobacter pylori: function and potential virulence effects. In: Goodwin CS, Worsley BW (ed):Helicobacter pylori: biology and clinical practice. CRC Press, Boca Raton, FL, 1993, p. 115–141.

    Google Scholar 

  67. Mendz GL, Hazell SL, Srinivasan S: Fumarate reductase: a target for therapeutic intervention againstHelicobacter pylori. Archives of Biochemistry and Biophysics 1995, 321: 153–159.

    Google Scholar 

  68. Covacci A, Censini S, Bugnoli M, Petracca R, Burroni D, Macchia G, Massone A, Papini E, Xiang ZY, Figura N, Rappuoli R: Molecular characterization of the 128-kDA immunodominant antigen ofHelicobacter pylori associated with cytotoxicity and duodenal ulcer. Proceedings of the National Academy of Sciences USA 1993, 90: 5791–5795.

    Google Scholar 

  69. Schmitt W, Haas R: Genetic analysis of theHelicobacter pylori vacuolating cytotoxin structural similarities with the IgA protease type of exported protein. Molecular Microbiology 1994, 12: 307–319.

    Google Scholar 

  70. Phadnis SH, Liver D, Janzon L, Normark S, Westblom TU: Pathological significance and molecular characterization of the vacuolating toxin gene ofHelicobacter pylori. Infection and Immunity 1994, 62: 1557–1565.

    Google Scholar 

  71. Crabtree JE, Farmery SM, Lindley IJD, Figura N, Peichl P, Tompkins DS: CagA/cytotoxic strains ofHelicobacter pylori and interleukin-8 in gastric epithelial cell lines. Journal of Clinical Pathology 1994, 47: 945–950.

    Google Scholar 

  72. Cover TL, Tummuru MKR, Cao P, Thompson SA, Blaser MJ: Divergence of genetic sequences for the vacuolating cytotoxin amongHelicobacter pylori strains. Journal of Biological Chemistry 1994, 269: 10566–10573.

    Google Scholar 

  73. Crowe SE, Alvarez L, Dytoc M, Hunt RH, Muller M, Sherman P, Patel J, Jin Y, Ernst PB: Expression of interleukin 8 and CD54 by human gastric epithelium afterHelicobacter pylori infectionin vitro. Gastroenterology 1995, 108: 65–74.

    Google Scholar 

  74. Lee A, O'Rourke J, Dixon M, Fox J: Helicobacter induced gastritis: look to the host. Acta Gastro-Enterologica Belgica 1993, 56, Supplement: 61.

    Google Scholar 

  75. Marchetti M, Arico B, Burroni D, Figura N, Rappuoli R, Ghiara P: Development of a mouse model ofHelicobacter pylori infection that mimics human disease. Science 1995, 267: 1655–1658.

    Google Scholar 

  76. Rautelin H, Kihlstrom E, Jurstrand M, Danielsson D: Adhesion to and invasion of HeLa cells byHelicobacter pylori. International Journal of Medical Microbiology 1995, 282: 50–53.

    Google Scholar 

  77. Wadström T, Ascencio F, Ljungh A, Lelwala-Guruge J, Ringer M, Utt M, Valkonen K:Helicobacter pylori adhesions. European Journal of Gastroenterology and Hepatology 1993, 5, Supplement 2: 12–15.

    Google Scholar 

  78. Nilius M, Bode G, Buchler M, Malfertheiner P: Adhesion ofHelicobacter pylori andEscherichia coli to human and bovine surface mucus cells in vitro. European Journal of Clinical Investigation 1994, 24: 454–458.

    Google Scholar 

  79. Rautelin H, Kihlström E, Jurstrand M, Danielsson D: Adhesion and invasion byHelicobacter pylori. Acta Gastro-Enterologica Belgica 1993, 56, Supplement: 119.

    Google Scholar 

  80. Owen RJ, Desai M, Figura N, Bayeli PF, Digregorio L, Russi M, Musmanno RA: Comparisons between degree of histological gastritis and DNA fingerprints, cytotoxicity and adhesivity ofHelicobacter pylori from different gastric sites. European Journal of Epidemiology 1993, 9: 315–321.

    Google Scholar 

  81. Kervella M, Pages JM, Pei ZH, Grollier G, Blaser MJ, Fauchere JL: Isolation and characterization of 2Campylobacter glycine-extracted proteins that bind to HeLa cell membranes. Infection and Immunity 1993, 61: 3440–3448.

    Google Scholar 

  82. Caselli M, Alvisi V: Bacterial adhesion andHelicobacter pylori. Gut 1991, 32: 111–112.

    Google Scholar 

  83. Wadström T, Guruge JL, Wei S, Aleljung P, Ljungh A:Helicobacter pylori hemagglutinins — possible gut mucosa adhesions. In: Malfertheiner P, Ditschuneit H (ed):Helicobacter pylori, gastritis and peptic ulcer. Berlin, Springer-Verlag, 1990, p. 96–103.

    Google Scholar 

  84. Rosberg K, Berglindh T, Gustavsson S, Hubinette R, Rolfsen W: Adhesion ofHelicobacter pylori to human gastric mucosal biopsy specimens cultivatedin vitro. Scandinavian Journal of Gastroenterology 1991, 26: 1179–1187.

    Google Scholar 

  85. Evans DG, Evans DJJ, Moulds JJ, Graham DY: N-acetylneuraminyllactose-binding fibrillar hemagglutinin ofCampylobacter pylori: a putative colonization factor antigen. Infection and Immunity 1988, 56: 2896–2906.

    Google Scholar 

  86. Falk PG, Bry L, Holgersson J, Gordon Jl: Expression of a human alpha-1,3/4-fucosyltransferase in the pit cell lineage of FVB/N mouse stomach results in production of Le(b)-containing glycoconjugates: a potential transgenic mouse model for studyingHelicobacter pylori infection. Proceedings of the National Academy of Sciences USA 1995, 92: 1515–1519.

    Google Scholar 

  87. Falk P, Roth KA, Boren T, Westblom TU, Gordon JI, Normark S: Anin vitro adherence assay reveals thatHelicobacter pylori exihibits cell lineage-specific tropism in the human gastric epithelium. Proceedings of the National Academy of Sciences USA 1993, 90: 2035–2039.

    Google Scholar 

  88. Boren T, Falk P, Roth KA, Larson G, Normark S: Attachment ofHelicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1993, 262: 1892–1895.

    Google Scholar 

  89. Handt LK, Fox JG, Dewhirst FE, Fraser GJ, Paster BJ, Yan LL, Rozmiarek H, Rufo R, Stalis IH:Helicobacter pylori isolated from the domestic cat: public health implications. Infection and Immunity 1995, 63: 1146.

    Google Scholar 

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Hazell, S.L. Isolation of “Helicobacter heilmannii” from human tissue. Eur. J. Clin. Microbiol. Infect. Dis. 15, 4–9 (1996). https://doi.org/10.1007/BF01586180

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