Specific effect of magnesium ion on 2′, 3′-cyclic amp synthesis from adenosine and trimeta phosphate in aqueous solution

  • Y. Yamagata
  • H. Inoue
  • K. Inomata


Phosphorylation of adenosine by trimetaphosphate was investigated using various catalysts in aqueous solution under mild conditions at pH ∼ 7.0 and at 41 °C. The product was primarily 2′,3′-cyclic AMP together with smaller amounts of ATP. Magnesium ion was found to have a remarkable catalytic effect of approximately one hundred times greater than the other chemicals tested. The mechanism for the specific effect of magnesium ion is discussed.


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Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Y. Yamagata
    • 1
  • H. Inoue
    • 2
  • K. Inomata
    • 3
  1. 1.Department of PhysicsKanazawa Institute of TechnologyIshikawaJapan
  2. 2.Department of PhysicsKanazawa UniversityKakuma, KanazawaJapan
  3. 3.Department of ChemistryKanazawa UniversityKakuma, KanazawaJapan

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