Summary
The plasma serotonin contents of fourty-three cerebrovascular patients were examined.
-
1.
Abnormal serotonin contents were found in 72 per cent of fourtythree cerebrovascular patients.
-
2.
In cerebral hemorrhage, serotonin contents were significantly low in the acute period.
-
3.
Serotonin contents in cerebral hemorrhage and subarachnoid hemorrhage, had an increasing tendency from the fourth week to the eighth week, but after the eighth week, they returned to normal.
Similar content being viewed by others
References
Arutiunov, A. I., Baron, M. A., Majorova, N. A. Experimental and clinical study of the development of spasm of the cerebral arteries related to subarachnoid hemorrhage. J. Neurosurg.32, 617–625 (1970).
Bogdanski, D. F., Pletscher, A., Brodie, B. B., Udenfriend, S. Identification and assay of serotonin in brain. J. Pharmacol. Exp. Ther.117, 82–88 (1956).
Brawley, B. W., Strandness, D. E., Kelly, W. A. The biphasic response of cerebral vasospasm in experimental subarachnoid hemorrhage. J. Neurosurg.28, 1–8 (1968).
Echlin, F. A. Spasm of basilar and vertebral arteries caused by experimental subarachnoid hemorrhage. J. Neurosurg.23, 1–11 (1965).
Raynor, R. B., McMurtry, J. G., Pool, J. L. Cerebrovascular effects of topically applied serotonin in the cat. Neurology (Minneap.)11, 190–195 (1961).
Welch, K. M. A., Meyer, J. S., Teraura, T., Hashi, K., Shinmaru, S. Ischemic anoxia and cerebral serotonin levels. J. Neurol. Sci.16, 85–92 (1972).
Welch, K. M. A., Hashi, K., Meyer, J. S. Cerebrovascular response to intracarotid injection of serotonin before and after middle cerebral artery occlusion. J. Neurol. Neurosurg. Psychiat.36, 724–735 (1973).
Wilkins, R. H., Silver, D., Odom, G. L. The role of circulating substances in intracranial arterial spasm. Neurology (Minneap.)16, 482–490 (1964).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ishizaki, F. Plasma serotonin contents in cerebrovascular disease. J. Neural Transmission 43, 133–141 (1978). https://doi.org/10.1007/BF01579072
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01579072