Summary
Morphometric reconstruction of 100 consecutive radical prostatectomy specimens were analyzed for tumor volume, complete capsular penetration (CP), seminal vesicle (SV) invasion, and lymph node (LN) metastasis. Tumors with a volume of <1 cc were completely confined within the prostate. Those with a volume of <4 cc were associated with a 21% incidence of CP, 5% SV invasion, and no LN metastasis. Tumors with a volume of >10 cc showed a 93% incidence of CP, 64% SV invasion, and 50% LN metastasis. When methods for accurate assessment of tumor volume become available, volume measurements should become an integral part of clinical staging in prostatic carcinoma.
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References
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Supported by a grant from the Richard M. Lucas Foundation
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Freiha, F., Redwine, E. Volume of detected disease and ability to effect cure by radical prostatectomy. World J Urol 7, 45–46 (1989). https://doi.org/10.1007/BF01576844
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DOI: https://doi.org/10.1007/BF01576844