Abstract
Lactobacillus curvatus SB13 biosynthetized during growth and excreted into the culture medium an inhibitor active againstListeria monocytogenes, Staphylococcus aureus, and some other Gram-positive bacteria. The native activity was linked to a non-dialyzable proteinaceous complex, destroyed by proteases, with an apparent molecular weight greater that 10 kDa. It showed a hydrophobic character, being soluble in alcohols and not denaturated by several organic solvents. The molecule was partially purified by ammonium sulfate precipitation and hydrophobic interaction chromatography.
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Sudirman, I., Mathieu, F., Michel, M. et al. Detection and properties of curvaticin 13, a bacteriocin-like substance produced byLactobacillus curvatus SB13. Current Microbiology 27, 35–40 (1993). https://doi.org/10.1007/BF01576831
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DOI: https://doi.org/10.1007/BF01576831