Skip to main content
SpringerLink
Log in

Structural basis for the association of heavy and light chains and the relation of subgroups to the conformation of the active site of immunoglobulins

  • Brief Communication
  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Capra, J.D. and Kehoe, J.M.: Distribution and association of heavy and light chain variable region subgroups among human IgA immunoglobulins.J. Immunol. 114:678–681, 1975

    Google Scholar 

  • Dayhoff, M.O. (ed.):Atlas of Amino Acid Sequence and Structure, Vol. 5, National Biomedical Research Foundation, Silver Spring, Md. 1972

    Google Scholar 

  • Poljak, R.J., Amzel, L.M., Avey, H.P., Chen, B.L., Phizackerley, R.P., and Saul, F.: Three-dimensional structure of the Fab' fragment of a human immunoglobulin at 2.8-Å resolution.Proc. Natl. Acad. Sci. USA 70:3305–3310, 1973

    Google Scholar 

  • Poljak, R.J., Amzel, L.M., Chen, B.L., Phizackerley, R.P., and Saul, F.: The three-dimensional structure of the Fab' fragment of a human myeloma immunoglobulin at 2.0-Å resolution.Proc. Natl. Acad. Sci. USA 71:3440–3444, 1974

    Google Scholar 

  • Segal, D.M., Padlan, E.A., Cohen, G.H., Rudikoff, S., Potter, M., and Davies, D.R.: The three-dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site.Proc. Natl. Acad. Sci. USA 71:4298–4305, 1974

    Google Scholar 

  • Stevenson, G.T. and Mole, L.E.: The specificity of chain interactions among immunoglobulins. Combination of γ chains with χ chains of the same subgroup as in the parent immunoglobulin G.Biochem. J. 139:369–374, 1974

    Google Scholar 

  • Weigert, M.G., Cesari, I.M., Yonkovich, S.J., and Cohn, M.: Variability in the lambda light chain sequences of mouse antibody.Nature 228:1045–1047, 1970

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biophysics, Johns Hopkins University School of Medicine, 21205, Baltimore, Maryland

    R. J. Poljak, L. M. Amzel, B. L. Chen, R. P. Phizackerley & F. Saul

Authors
  1. R. J. Poljak
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. M. Amzel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. L. Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. P. Phizackerley
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. Saul
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Poljak, R.J., Amzel, L.M., Chen, B.L. et al. Structural basis for the association of heavy and light chains and the relation of subgroups to the conformation of the active site of immunoglobulins. Immunogenetics 2, 393–394 (1975). https://doi.org/10.1007/BF01572309

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01572309

Keywords

Search

Navigation