Abstract
Studies with congenic resistant strains of mice indicate that susceptibility to Rous sarcoma virus tumorigenesis is influenced by a gene or genes associated with the major histocompatibility complex (H-2). These genes manifest dominant relative susceptibility. Preliminary studies indicate that the CBA/J strain harbors a gene or genes for relative susceptibility, which are recessive. These results are compared with other studies onH-2-associated genes affecting murine viral oncogenesis.
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Whitmore, A.C., Haughton, G. Genetic control of susceptibility of mice to Rous sarcoma virus tumorigenesis. Immunogenetics 2, 379–388 (1975). https://doi.org/10.1007/BF01572307
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DOI: https://doi.org/10.1007/BF01572307