Abstract
The genetic control of susceptibility to experimental allergic encephalomyelitis (EAE) was studied in mice. The results indicate that sensitivity to disease is not inherited in a simple Mendelian dominant way. Susceptibility to EAE is governed by genes located outside of the major histocompatibility complex and not byH-2-linkedIr genes. No correlation was observed between susceptibility to disease and the cellular immune response toward the small encephalitogenic protein.
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Lando, Z., Teitelbaum, D. & Arnon, R. Genetic control of susceptibility to experimental allergic encephalomyelitis in mice. Immunogenetics 9, 435–442 (1979). https://doi.org/10.1007/BF01570436
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DOI: https://doi.org/10.1007/BF01570436