Abstract
Basal serum levels of IgA in the congenic mice C57BL/10 and C57BL/10. F are shown to be different. The levels of IgA of the reciprocal F1 hybrids are also different. When the female parent of the hybrid is from the high strain (B10), the F1 is high; and when the female parent is from the low strain (B10.F), the F1 is low. Backcross and F2 progeny were raised from the two F1 hybrids, serotyped for H-2 antigens, and assayed for IgA level. Evidence for linkage of IgA phenotype could be demonstrated only with progeny from the F1 hybrid that exhibited the low IgA phenotype. The maternal effect is not due to a sex-linked, recessive gene.
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Popp, D.M. Basal serum immunoglobulin levels. Immunogenetics 9, 281–292 (1979). https://doi.org/10.1007/BF01570422
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DOI: https://doi.org/10.1007/BF01570422