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Interactions ofCandida albicans with bacteria and salivary molecules in oral biofilms

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Journal of Industrial Microbiology

Abstract

The yeastCandida albicans coaggregates with a variety of streptococcal species, an interaction that may promote oral colonization by yeast cells.C. albicans andCandida tropicalis are the yeasts most frequently isolated from the human oral cavity and our data demonstrate that both these species bind toStreptococcus gordonii NCTC 7869 while two otherCandida species (Candida krusei andCandida kefyr) do not. Adherence ofC. albicans was greatest when the yeast had been grown at 30° C to mid-exponential growth phase. For 21 strains ofC. albicans there was a positive correlation between the ability to adhere toS. gordonii and adherence to experimental salivary pellicle. Whole saliva either stimulated or slightly inhibited adherence ofC. albicans toS. gordonii depending on the streptococcal growth conditions. The results suggest that the major salivary adhesins and coaggregation adhesins ofC. albicans are co-expressed.

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Authors and Affiliations

  1. Department of Oral Biology and Oral Pathology, University of Otago, PO Box 647, Dunedin, New Zealand

    AR Holmes, RD Cannon & HF Jenkinson

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  1. AR Holmes
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  2. RD Cannon
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  3. HF Jenkinson
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Holmes, A., Cannon, R. & Jenkinson, H. Interactions ofCandida albicans with bacteria and salivary molecules in oral biofilms. Journal of Industrial Microbiology 15, 208–213 (1995). https://doi.org/10.1007/BF01569827

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  • DOI: https://doi.org/10.1007/BF01569827

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