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Altered rate of synthesis of specific peptides in the legionellae in response to growth temperature

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Abstract

The effect of a sharp temperature rise (30° to 42°C) on the rate of peptide synthesis inLegionella pneumophila (three strains),Tatlockia micdadei (Tatlock), andFluoribacter bozemanae (WIGA) was examined. Most striking was an increase in the rate of synthesis of 4–5 peptides of approximate molecular weight 85,000 daltons (85k), 78k, 70k, and either 60k (only in theL. pneumophila strains and WIGA) or 62.5k, and 40k (only in Tatlock). The response required new mRNA synthesis. In addition, the heat shock response of these organisms continued as long as the high temperature condition persisted (at least 24 h) and for at least 1 h after temperature downshift (to 30°C).

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Authors and Affiliations

  1. Research Service, WJB Dorn Veterans' Hospital, Garners Ferry Road, 29201, Columbia, SC, USA

    Michael W. Lema,  Arnold Brown & Grace C. C. Chen

  2. Department of medicine and Microbiology/Immunology, University of South Carolina School of Medicine, Columbia, South Carolina, USA

    Arnold Brown

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  1. Michael W. Lema
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  2. Arnold Brown
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  3. Grace C. C. Chen
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Lema, M.W., Brown, A. & Chen, G.C.C. Altered rate of synthesis of specific peptides in the legionellae in response to growth temperature. Current Microbiology 12, 347–352 (1985). https://doi.org/10.1007/BF01567895

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