Abstract
Rhizobium trifolii was highly resistant to the lethal effect ofN-methyl-N′-nitro-N-nitrosoguanidine (MNNG), but it was sensitive to the mutagenic action of this chemical. A concentration of 500μg/ml yields a survival of between 1% and 10%, which allows us to obtain a higher number of mutants than lower concentrations that yield higher survival rates. Lethal damage produced by nitrosoguanidine was repaired, and repair is inhibited by acriflavine.
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Megias, M., Caviedes, M.A., Rodriguez-Quiñones, F. et al. Action ofN-methyl-N′-nitro-N-nitrosoguanidine inRhizobium trifolii . Current Microbiology 12, 325–328 (1985). https://doi.org/10.1007/BF01567891
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DOI: https://doi.org/10.1007/BF01567891