Abstract
Serological characterization of threeK-S interval recombinant strains, TBR2 (H-2 at2), TBR3 (H-2 at3) and AIR1 (H-2 a2) was performed using anti-H-2, Ia, Ss and Slp antisera. The data presented here reveal that the crossover events in both TBR2 and TBR3 occurred between theI-A andI-E subregions. In both cases, theH-2K andI-A subregions were derived from theH-2 t1 chromosome, while theI-E, S andH-2D regions were derived from theH-2 b chromosome (K s A k E b S b D b). TheH-2 a2 chromosome resulted from a crossover event between theH-2 a1 andH-2 i9 chromosomes. Ia and Ss typing of AIR1 suggested that theK toI-E regions originated fromH-2 a1 and theS andD regions originated fromH-2 i9 (K k A k E k S b D d).
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Beisel, K.W., Passmore, H.C. & David, C.S. Intra-H-2 recombination in the mouse. Immunogenetics 11, 123–130 (1980). https://doi.org/10.1007/BF01567778
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DOI: https://doi.org/10.1007/BF01567778