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Ultrastructure and cell wall chemistry of a thermosensitive mutant ofParacoccidioides brasiliensis

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Abstract

Results of chemical analysis and ultrastructural study of the cell wall of a thermosensitive dimorphic mutant ofParacoccidioides brasiliensis support the involvement of α-1,3-glucan in the process of dimorphism, but do not support a possible role of this glucan as being responsible for the yeast-like morphology of this pathogenic fungus.

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Literature Cited

  1. Carbonell, L. M. 1969. Ultrastructure of dimorphic transformation inParacoccidioides brasiliensis. Journal of Bacteriology100:1076–1082.

    PubMed  Google Scholar 

  2. Carbonell, L. M., Pollak, L. 1963. Ultraestructural delParacoccidioides brasiliensis en cultivos de la fase levaduriforme. Mycopathologia et Mycologia Applicata19:184–204.

    PubMed  Google Scholar 

  3. Carbonell, L. M., Rodríguez, J. 1965. Transformation of mycelial and yeast forms ofParacoccidioides brasiliensis in culture and in experimental inoculations. Journal of Bacteriology90:504–510.

    PubMed  Google Scholar 

  4. Carbonell, L. M., Rodríguez, J. 1968. Mycelial phase ofParacoccidioides brasiliensis andBlastomyces dermatitidis: an electron microscope study. Journal of Bacteriology96:533–543.

    PubMed  Google Scholar 

  5. Furtado, J. S., de Brito, T., Freymuller, E. 1967. The structure and reproduction ofParacoccidioides brasiliensis in human tissue. Sabouraudia5:226–229.

    PubMed  Google Scholar 

  6. Hallak, J., San-Blas, F., San-Blas, G. 1982. Isolation and wall analysis of dimorphic mutants ofParacoccidioides brasiliensis. Sabouraudia20:51–62.

    PubMed  Google Scholar 

  7. Kanetsuna, F., Carbonell, L. M., Azuma I., Yamamura, Y. 1972. Biochemical studies on the thermal dimorphism ofParacoccidioides brasiliensis. Journal of Bacteriology110:208–218.

    PubMed  Google Scholar 

  8. Nickerson, W. J. 1948. Enzymatic control of cell division in microorganisms. Nature (London)162:241–245.

    Google Scholar 

  9. Restrepo, A. 1970. A reappraisal of the microscopical, appearance of the mycelial phase ofParacoccidioides brasiliensis. Sabouraudia8:141–144.

    PubMed  Google Scholar 

  10. Reynolds, E. S. 1963. Use of lead citrate at high pH as an electron opaque stain in electron microscopy. Journal of Cell Biology17:208–213.

    PubMed  Google Scholar 

  11. San-Blas, F., San-Blas, G., Inlow, D. 1980. Dimorphism inParacoccidioides brasiliensis, pp. 23–28. In: H. J. Preusser (ed.), Medical Mycology: Proceedings of the Mycological Symposia of the XII International Congress of Microbiology, Munich. Stuttgart: Gustav Fischer Verlag.

    Google Scholar 

  12. San-Blas, G., Carbonell, L. M. 1974. Chemical and ultrastructural studies on cell walls of the yeastlike and mycelial forms ofHistoplasma farciminosum. Journal of Bacteriology119:602–611.

    PubMed  Google Scholar 

  13. San-Blas, G., San-Blas, F. 1977.Paracoccidioides brasiliensis: cell wall structure and virulence. Mycopathologia62:77–86.

    PubMed  Google Scholar 

  14. Watson, M. L. 1958. Staining of tissue sections for electron microscopy with heavy metals. Journal of Biophysical and Biochemical Cytology4:475–480.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas (IVIC), Apartado 1827, 1010A, Caracas, Venezuela

    Felipe San-Blas, Gioconda San-Blas, Joseph Hallak & Enrique Merino

Authors
  1. Felipe San-Blas
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  2. Gioconda San-Blas
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  3. Joseph Hallak
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  4. Enrique Merino
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San-Blas, F., San-Blas, G., Hallak, J. et al. Ultrastructure and cell wall chemistry of a thermosensitive mutant ofParacoccidioides brasiliensis . Current Microbiology 8, 85–88 (1983). https://doi.org/10.1007/BF01566963

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