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Influence of β-lactam antibiotics in vitro on mixed cultures ofEscherichia coli andStreptococcus faecalis

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Abstract

The effect of β-lactams in vitro on mixed cultures ofEscherichia coli andStreptococcus faecalis was studied by monitoring the time-dependent course of antibacterial action of ampicillin, mezlocillin, piperacillin, and cefotaxime. These tests revealed that ampicillin and especially mezlocillin acted bactericidally againstE. coli andS. faecalis; piperacillin and cefotaxime selectedS. faecalis from mixed cultures. This behavior suggests interference with the natural balance between the two species.

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  1. Institute for Chemotherapy, Bayer AG, P.O. Box 101709, D-5600, Wuppertal-1, Germany

    Axel Dalhoff

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  1. Axel Dalhoff
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Dalhoff, A. Influence of β-lactam antibiotics in vitro on mixed cultures ofEscherichia coli andStreptococcus faecalis . Current Microbiology 7, 269–274 (1982). https://doi.org/10.1007/BF01566861

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