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Ly-5: A new T-lymphocyte antigen system


Ly-5 is a third genetic locus of the type so far represented in the mouse byLy-1 andLy-2/Ly-3; it specifies antithetical alloantigens, one of which is present exclusively on T lymphocytes of every mouse. The chromosomal locus ofLy-5 has not been established, but it is not closely linked toLy-1 orLy-2/Ly-3. Like other T-lymphocyte surface markers, expression of Ly-5 antigens on T-lymphocyte precursor cells can be initiated in vitro by inducers of T-cell differentiation.

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Recipient of a fellowship from the New York Cancer Research Institute, Inc.

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Komuro, K., Itakura, K., Boyse, E.A. et al. Ly-5: A new T-lymphocyte antigen system. Immunogenetics 1, 452–456 (1974).

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  • Precursor Cell
  • Surface Marker
  • Chromosomal Locus
  • Genetic Locus
  • Antigen System