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Immunogenetics

, Volume 1, Issue 1, pp 452–456 | Cite as

Ly-5: A new T-lymphocyte antigen system

  • K. Komuro
  • K. Itakura
  • E. A. Boyse
  • M. John
Article

Abstract

Ly-5 is a third genetic locus of the type so far represented in the mouse byLy-1 andLy-2/Ly-3; it specifies antithetical alloantigens, one of which is present exclusively on T lymphocytes of every mouse. The chromosomal locus ofLy-5 has not been established, but it is not closely linked toLy-1 orLy-2/Ly-3. Like other T-lymphocyte surface markers, expression of Ly-5 antigens on T-lymphocyte precursor cells can be initiated in vitro by inducers of T-cell differentiation.

Keywords

Precursor Cell Surface Marker Chromosomal Locus Genetic Locus Antigen System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1975

Authors and Affiliations

  • K. Komuro
    • 1
  • K. Itakura
    • 1
  • E. A. Boyse
    • 1
  • M. John
    • 1
  1. 1.Memorial Sloan-Kettering Cancer CenterNew York

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