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Experimental allergic encephalomyelitis in congenic strains of mice

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Abstract

Inbred mice and lines congenic to them for the major histocompatibility complex were similar in susceptibility to EAE except for moderate differences in two pairs. TheH-2 haplotypesq, s, andb occurred in inbred strains and in congenic lines of high, medium, or low susceptibility. It is concluded that the major histocompatibility complex does not control susceptibility to EAE in mice. Furthermore, the low susceptibility of DBA/1J mice was not enhanced by poly A-U.

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Authors and Affiliations

  1. Pathology Department, New York Medical College Center for Chronic Disease Bird S. Coler Hospital Roosevelt Island, New York, New York

    Seymour Levine & Richard Sowinski

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  1. Seymour Levine
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  2. Richard Sowinski
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Levine, S., Sowinski, R. Experimental allergic encephalomyelitis in congenic strains of mice. Immunogenetics 1, 352–356 (1974). https://doi.org/10.1007/BF01564073

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  • DOI: https://doi.org/10.1007/BF01564073

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