Skip to main content
Log in

A note on the occurrence of ruptured duodenal ulcer in two patients previously treated with metrazol

  • Scientific Contributions
  • Published:
Psychiatric Quarterly Aims and scope Submit manuscript

Summary

Two cases of ruptured duodenal ulcer occurring in patients previously treated with metrazol are described. The theory that there may be a causal relationship between the preceding metrazol therapy and the later gastrointestinal pathology is advanced.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Friedman, E.: The irritative treatment of schizophrenia. Am. J. Psychiat., 94:355, September, 1937.

    Google Scholar 

  2. Winkelman, N. W.: Metrazol treatment in schizophrenia. Ibid, 95:303, September, 1938.

    Google Scholar 

  3. Polatin, P., Friedman, M. M., Harris, M. M. and Horowitz, W. A.: Vertebral fractures produced by metrazol-induced convulsions. J. A. M. A., 112:17, April 29, 1939.

    Google Scholar 

  4. Bennett, B. T., Jr. and Fitzpatrick, C. P.: Fractures of spine complicating metrazol therapy. Ibid 112:2240, June 3, 1939.

    Google Scholar 

  5. Goldstein, H. H., Dombrowski, E. F., Edlin, J. V., Bay, A. P., McCorry, C. V. and Weinberg, J.: Treatment of psychoses with pentamethylenetetrazol. Am. J. Psychiat., 94:1347, May, 1938.

    Google Scholar 

  6. Somers, D. C. and Richardson, R. D.: Bilateral fracture of the femoral necks caused by metrazol convulsions. Ibid 95:1193, March, 1939.

    Google Scholar 

  7. Homsa, W. R. and Bennett, A. E.: Traumatic complications of convulsive shock therapy J. A. M. A., 112:2244, June 3, 1939.

    Google Scholar 

  8. Dick, A. and McAdam, W.: Cardiac complications in cardiazol treatment: observations in four cases. J. Ment. Sci., 84:999, November, 1938.

    Google Scholar 

  9. Pellens, M.: Electrocardiographic studies of patients receiving convulsive doses of metrazol in the treatment of schizophrenia.Psychiat. Quart., 12:722, 1938.

    Google Scholar 

  10. Gross, M. and Gross-May, G.: Accidents in the course of metrazol therapy of schizophrenic patients. J. Belge de neurol. et de psychiat., 39:336, May, 1939.

    Google Scholar 

  11. Cushing, H.: Peptic ulcers and the interbrain. Surg. Gynec. and Obstet., 55:1, 1932.

    Google Scholar 

  12. Masten, M. G. and Bunts, R. C.: Neurogenic erosions and perforations of the stomach and esophagus in cerebral lesions. Arch. Int. Med., 54:916, December, 1934.

    Google Scholar 

  13. Grant, F. C.: Brain lesions and duodenal ulcer. Am. Surg. 101:156, January, 1935.

    Google Scholar 

  14. Vonderahe, A. R.: Histopathologic changes in the nervous system in cases of peptic ulcer. Arch. Neurol. and Psychiat., 41:871, May, 1939.

    Google Scholar 

  15. Strecker, E. A., Alpers, B. J., Flaherty, J. A. and Hughes, J.: Experimental and clinical study of the effects of metrazol convulsions. Ibid 41:996, May, 1939.

    Google Scholar 

  16. Liebert, E. and Weil, A.: Histopathologic changes in the brain following experimental injections of metrazol. Ibid 42:690, October, 1939.

    Google Scholar 

  17. Cleckley, H., Bowles, L. and Mettler, F. A.: Histologic changes following metrazol convulsions. Ibid 43:948, May, 1940.

    Google Scholar 

  18. Hassin, G. B.: Cerebral changes in fatal cases following treatment with barbital, soluble barbital, U. S. P. insulin and metrazol. Ibid 42:679, October, 1939.

    Google Scholar 

  19. Fulton, J. F.: Physiology of the Nervous System. Oxford University Press, New York, 1938.

    Google Scholar 

  20. Richter, E. B. and Traut, E. F.: Chronic encephalitis: pathologic report of a case with protracted somnolence. Arch. Neurol. and Psychiat., 44:848, October, 1940.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moore, C.D., Friedman, S. A note on the occurrence of ruptured duodenal ulcer in two patients previously treated with metrazol. Psych Quar 15, 380–386 (1941). https://doi.org/10.1007/BF01563339

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01563339

Keywords

Navigation