Summary
Thirteen patients receiving modified ECT for structural reasons, were given flaxedil to obtain reduced grand mal seizures. A dosage of 1.5 to 2.5 ccs. was found adequate to modify the convulsion; the therapeutic effect of ECT, using the technique outlined in this report, was not interfered with by flaxedil.
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Bennett, A. E.: Curare, a preventive of traumatic complications in convulsive shock therapy. Am. J. Psychiat., 97:100, 1941.
Cash, P. T., and Hoekstra, C. S.: Preliminary curarization in electric convulsive shock therapy.Psychiat. Quart., 17:20, 1943.
Easton, N. L., and Sommers, J.: The significance of vertebral fractures as a complication of metrazol therapy. Am. J. Psychiat., 98:538, 1942.
Ebaugh, F. C.; Barancle, C. H.; and Neuburger, K. T.: Fatalities following electric convulsive therapy. Arch. Neurol. and Psychiat., 49:107, 1943.
Furst, W.: The force required to crush vertebrae.Psychiat. Quart., 14:397, 1940.
Holt, W. L., Jr.: Modifications of electric shock therapy.Psychiat. Quart., 26:353, 1952. [Editorial note: Dr. Holt's paper was published after Drs. Neander and Alexander had completed their present paper, and had submitted it for editorial consideration.]
Kalinowsky, L., and Hoch, P.: Shock Treatments and Other Somatic Procedures in Psychiatry. Grune & Stratton. New York. 1946.
Noyes, Arthur P.: Modern Clinical Psychiatry. 3d edition. Saunders. Philadelphia. 1948.
Newsletter Bulletin—Lederle Laboratories: The use of flaxedil.
Kinsey, L. J.: Incidence and cause of death in shock therapy. Arch. Neurol. and Psychiat., 46:55, 1941.
Polatin, P.; Friedman, M. M.; Harris, M. M.; and Horwitz, W. A.: Vertebral fractures produced by metrazol induced convulsions in treatment of psychiatric disorders. J. A. M. A., 112:1684, 1939.
Reed, G. E., and Dancey, T. E.: Compression fractures of the vertebral bodies following induced and “idiopathic” convulsions. Canad. Med. Asso. J., 42:38, 1940.
Stalker, H.: Double compression fracture from convulsive therapy. Lancet, 2:1172, 1938.
Worthing, H. W., and Kalinowsky, L. B.: The question of vertebral fractures in convulsive therapy and in epilepsy. Am. J. Psychiat., 98:533, 1942.
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Read at the Upstate Interhospital Conference, Syracuse Psychopathic Hospital, Syracuse, N. Y., April 23, 1952.
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Neander, J.F., Alexander, S.P. A preliminary study on the use of flaxedil. Psych Quar 27, 83–89 (1953). https://doi.org/10.1007/BF01562477
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DOI: https://doi.org/10.1007/BF01562477