References
Biddison, W. E., Hansen, T. H., Levy, R. B., and Doherty, P. C.: Involvement ofH-2Lgene products in virus-immune T-cell recognition.J. Exp. Med. 148: 1678–1686, 1978
Blanden, R. V., McKenzie, I. F. C., Kees, U., Melvold, R. W., and Kohn, H. I.: Cytotoxic T-cell response to ectromelia virus-infected cells. Different H-2 requirements for triggering precursor T-cell induction or lysis by effector T-cells defined by the BALB/c-H-2 db mutation.J. Exp. Med. 146: 869–880, 1977
Blanden, R. V. and Kees, U.: Cytotoxic T-cell responses show more restricted specificity for self than for non-selfH-2D-coded antigens.J. Exp. Med. 147: 1661–1670, 1978
Burnet, F. M. and Boake, W. C.: The relationship between the virus of infectious ectromelia of mice and vaccinia virus.J. Immunol. 53: 1–13, 1946
Coligan, J. E., Kindt, T. J., Nairn, R., Nathenson, S. G., Sachs, D. H. and Hansen, T. H.: Primary structural studies of anH-2L molecule confirms that it is unique and homologous toH-2K andH-2D antigens.Proc. Natl. Acad. Sci., in press, 1979
Forman, J.: On the role of theH-2 histocompatibility complex in determining the specificity of cytotoxic cells sensitized against syngeneic TNP modified targets.J. Exp. Med. 142: 403–418, 1975
Forman, J. and Flaherty, L.: Identification of a new CML target antigen controlled by a gene associated with theQa-2 locus.Immunogenetics 6: 227–233, 1978
Gardner, I. Bowern, N. A., and Blanden, R. V.: Cell mediated cytotoxicity against ectromelia virus-infected target cells. I. specificity and kinetics.Eur. J. Immunol. 4: 63–67, 1974
Hansen, T. H., Cullen, S. E., and Sachs, D. H.: Immunochemical evidence for an additional H-2 region closely linked to H-2D.J. Exp. Med. 146: 438–442, 1977a
Hansen, T. H., Cullen, S. E., Melvold, R., Kohn, H., Flaherty, L., and Sachs, D. H.: Mutation in a new H-2-associated histocompatibility gene closely linked to H-2D.J. Exp. Med. 145: 1550–1558, 1977b
Hansen, T. H. and Sachs, D. H.: Isolation and antigenic characterization of the product of a third polymorphic H-2 locus,H-2L.J. Immunol. 121: 1469–1472, 1978
Hansen, T. H. and Levy, R. B.: Alloantigens determined by a secondD region locus elicit a strong in vitro cytotoxic response.J. Immunol. 120: 1836–1840, 1978
Hansen, T. H., Iványi, P., Levy, R. B., and Sachs, D. H.: Cross reactivity among the products of three non-allelic H-2 loci,H-2L d,H-2D q andH-2K k.Transplantation 28: 339–342, 1979
Iványi, P., Melief, C. J. M., Greeve, P., and Mourik, P.: Individual mice recognize the complex nature of H-2 antigens: unexpected reactions (anti-Kk) in the anti-BALB/c-H-2d sera produced in the BALB/c-H-2db mutant.Transplant. Proc. 11: 642–646, 1978
Kastner, D. L. and Rich, R. R.: H-2-nonrestricted cytotoxic responses to an antigen encoded telomeric toH-2D.J. Immunol. 122: 196–201, 1979
Klein, J., Geib, R., Chiang, C.-L., and Hauptfeld, V.: Histocompatibility antigens controlled by theI region of the murine H-2 complex. I. mapping ofH-2A andH-2C loci.J. Exp. Med. 143: 1439–1452, 1976
Klein, J. and Chiang, C.: A new locus (H-2T) at theD end of theH-2 complex.Immunogenetics 6: 235–243, 1978
Lemonnier, F., Neauport-Sautes, C., Kourilsky, F. M. and Démant, P.: Relationships between private and public H-2 specificities on the cell surface.Immunogenetics 2: 517–529, 1975
Lemmonier, F., Burakoff, S. J., Germain, R. N., and Benacerraf, B.: Cytolytic thymus-derived lymphocytes specific for allogeneic stimulator cells crossreact with chemically modified syngeneic cells.Proc. Natl. Acad. Sci. U.S.A. 74: 1229–1233, 1977
Levy, R. B., Shearer, G. M., and Hansen, T. H.: Properties ofH-2L locus products in allogeneic and H-2 restricted, trinitrophenyl-specific cytotoxic responses.J. Immunol. 121: 2263–2269, 1978
Levy, R. B. and Shearer, G. M.: Regulation of T-cell-mediated lympholysis by the murine major histocompatibility complex. I. Preferential in vitro response to trinitrophenyl-modified self K- and D-coded gene products in parental andF 1 hybrid mouse strains.J. Exp. Med. 149: 1379–1392, 1979
Levy, R. B. and Shearer, G. M.: Regulation of T-cell mediated lympholysis by the murine major histocompatibility complex. II. Control of cytotoxic responses trinitrophenyl-K and -D selfproducts of H-2K and H-2D region genes.J. Exp. Med., in press, 1979
Lindahl, K. F.: Unrestricted killer cells recognize an antigen controlled by a gene linked toTla.Immunogenetics 8: 71–76, 1979
McKenzie, I. F. C., Morgan, G. M., Melvold, R. W., and Kohn, H. L.: BALB/c-H-2 db: a new H-2 mutant in BALB/cKh that identifies a locus associated with theD region.Immunogenetics 4: 333–347, 1977
Nairn, R. and Nathenson, S. G.: Structural studies of theH-2D products of the mouse mutant BALB/c-H-2Ddb and the parental strain BALB/cKh-H-2Dd.J. Immunol. 121: 869–871, 1978
Neauport-Sautes, C., Morello, D., Freed, J., Nathenson, S. G., and Demant, P.: The private specificity H-2.4 and the public specificity H-2.28 of theD region are expressed on two different polypeptide chains.Eur. J. Immunol. 7: 511–515, 1977
Schmitt-Verhulst, A. M., and Shearer, G. M.: Multiple H-2 linked immune response gene control of H-2D associated T-cell mediated lympholysis to trinitrophenyl-modified autologous cells: Ir-like genes mapping to the left ofI-A and within theI-region.J. Exp. Med. 144: 1701–1706, 1976
Shearer, G. M.: Cell mediated cytoxicity to trinitrophenyl modified syngeneic lymphocytes.Eur. J. Immunol. 4: 527–533, 1974
Shearer, G. M., Rehn, T. G., and Garbarino, C. A.: Cell-mediated lynpholysis of Triphenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by theH-2K andH-2D serological regions of the murine major histocompatibility complex.J. Exp. Med. 141: 1348–1364, 1975
Wernet, D. and Klein, J.: Unrestricted cell-mediated lympholysis to antigens linked to theTla locus in the mouse.Immunogenetics 8: 361–365, 1979
Zinkernagel, R. M. and Doherty, P. C.: H-2 compatibility requirement for T-cell mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T-cell specificities are associated with structures coded for inH-2K andH-2D.J. Exp. Med. 141: 1427–1436, 1975
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Levy, R.B., Hansen, T.H. Functional studies of the products of theH-2L locus. Immunogenetics 10, 7–17 (1980). https://doi.org/10.1007/BF01561548
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01561548