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Should hyperthyroidism be treated by surgery?

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Abstract

Although radioactive iodine has been shown to be an effective nonsurgical treatment for hyperthyroidism, surgery remains a major treatment methodology. Nodular goiters with hyperthyroidism, which are still common in Scandinavia and elsewhere in Europe, are most effectively treated with surgery. The carcinogenic effects of131I have not been fully determined; until a large- scale, long- term controlled study of patients treated with131I is performed to establish the role of radioactive iodine in the development of carcinoma, its complete worldwide use is not recommended. There is low postoperative recurrence, mortality and morbidity with surgery for hyperthyroidism as performed in Scandinavia.

Résumé

Bien que l'iode radioactif soit une forme de traitement non opératoire efficace de l'hyperthyroïdie, la chirurgie reste le principal mode thérapeutique: elle est particulièrement utile dans les goitres nodulaires avec hyperthyroïdie, qui sont encore fréquents en Scandinavie et dans le reste de l'Europe. Les effets carcinogènes de131I n'ont pas encore été précisés. Son usage généralisé n'est donc pas justifié, aussi longtemps qu'une étude contrôlée à grande échelle et à long terme n'aura pas défini cet effet carcinogène. Après la chirurgie, telle qu'elle est faite en Scandinavie, les récidives sont rares, la mortalité et la morbidité sont faibles.

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Heimann, P. Should hyperthyroidism be treated by surgery?. World J. Surg. 2, 281–283 (1978). https://doi.org/10.1007/BF01561492

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  • DOI: https://doi.org/10.1007/BF01561492

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