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Heptachlor induced changes in fenitrothion metabolism

Summary

Pretreatment of rats with heptachlor administered in the food for 3 months increases the metabolism of fenitrothion. Comparison of oxon analogue levels in the blood and livers of pretreated and control animals suggests that the conversion of fenitrothion to its oxon analogue is enhanced and accelerated. This was studied by tracer methods, using P-fenitrothion.

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Mestitzova, M., Kovac, J. & Durcek, K. Heptachlor induced changes in fenitrothion metabolism. Bull. Environ. Contam. Toxicol. 5, 195–201 (1970). https://doi.org/10.1007/BF01558309

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Keywords

  • Petroleum Ether
  • Liver Weight
  • Oxon
  • Heptachlor
  • Filter Cake