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Use of chlorpromazine in the treatment of adynamic ileus

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Abstract

Ten patients suffering from severe adynamic ileus which did not respond to standard treatment, consisting of nasogastric suction and neostigmine, received chlorpromazine either intravenously or intramuscularly in association with neostigmine. This therapy was successful in 8 patients and failed in 2. One 89-year-old woman developed a cecal perforation. This complication could presumably have been avoided with a “blow hole” cecostomy.

Résumé

Dix malades atteints d'un iléus paralytique grave ne répondant pas au traitement classique-aspiration gastrique et néostigmine-ont été traités à la chlorpromazine intraveineuse ou intramusculaire associée à la néostigmine. Le traitement a été efficace dans 8 cas; il a échoué dans 2 cas. Une malade de 89 ans a présenté une perforation caecale qui aurait vraisemblablement pu Être évitée par une caecostomie de décharge.

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Supported by the Fonds de la Recherche Scientifique et Médicale.

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Kinnaert, P., Panda, M. & Deuvaert, F. Use of chlorpromazine in the treatment of adynamic ileus. World J. Surg. 1, 655–658 (1977). https://doi.org/10.1007/BF01556202

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  • DOI: https://doi.org/10.1007/BF01556202

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