Skip to main content
SpringerLink
Log in

Comparative cytopathology of canine distemper and measles viruses in ferret kidney cell cultures

  • Published:
Archiv für die gesamte Virusforschung Aims and scope Submit manuscript

Summary

Multinucleated giant cells, cytoplasmic and intranuclear inclusions were characteristic findings in ferret kidney cultures inoculated with canine distemper virus. Variations observed among strains were of a quantitative nature and these did not serve as distinguishing features. Contracted giant cells were observed which were interpreted as being degenerative forms of the multinucleated giant cells. Ferret kidney cell cultures inoculated with measles virus showed the same characteristics.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Pereira, H. G.: The cytopathic effect of animal viruses. In: Advances in Virus Research8 (1961).

  2. Enders, J. F., andT. C. Peebles: Propagation in tissue cultures of cytopathogenic agents from patients with measles. Proc. Soc. Exp. Biol. Med.86, 277–286 (1954).

    PubMed  Google Scholar 

  3. Milovanovic, M. V., J. F. Enders, andA. Mitus: Cultivation of measles virus in human amnion cells and in developing chick embryo. Proc. Soc. Exp. Biol. Med.95, 120–127 (1957).

    PubMed  Google Scholar 

  4. Plowright, W., andR. D. Ferris: Studies with rinderpest virus in tissue culture. I. Growth and cytopathogenicity. J. Comp. Path. Therap.69, 152–172 (1959).

    Google Scholar 

  5. Lasfargues, E., andJ. Lasfargues: Inclusions cytoplasmiques provoquées par l'agent de la maladie de Carré dans les fibroblastes d'embryon de poulet cultivés „in vitro“. Compt. Rend. Acad. Sci.146, 1711–1713 (1952).

    Google Scholar 

  6. Reculard, P., L. Nicol, O. Girard, R. Corvazier, M. Cheyroux, andPh. Sizaret: Etude du virus de Carré en cultures cellulaires. I. Culture du virus sur cellules embryonnaires de poulet. Ann. Inst. Pasteur98, 344–350 (1960).

    Google Scholar 

  7. Bussell, R. H., andD. T. Karzon: Canine distemper virus in chick embryo cell culture. Plaque assay, growth and stability. Virology18, 589–600 (1962).

    PubMed  Google Scholar 

  8. Rockborn, G.: Canine distemper virus in tissue culture. Arch. ges. Virusforsch.8, 485–492 (1958).

    Google Scholar 

  9. Hopper, P. K.: The propagation of canine distemper virus in tissue culture. J. Comp. Path.69, 78–86 (1959).

    PubMed  Google Scholar 

  10. Vantsis, J. T.: Preliminary note on the propagation of canine distemper virus in different tissue culture systems. Vet. Rec.71, 99–100 (1959).

    Google Scholar 

  11. Bussell, R. H., andD. T. Karzon: Study of canine distemper virus strains in several cell culture systems. Bact. Proc. p. 132 (1962).

  12. Bittle, J. L., C. J. York, andJ. W. Newberne: Adaptation and modification of a strain of canine distemper virus in tissue culture. Cornell Vet.51, 359–369 (1961).

    Google Scholar 

  13. Shaver, D. N., A. L. Barron, andD. T. Karzon: Cytopathology of human enteric viruses in tissue culture. Am. J. Path.34, 943–963 (1958).

    PubMed  Google Scholar 

  14. Reissig, M., D. W. Howes, andJ. L. Melnick: Sequence of morphological changes in epithelial cell cultures infected with poliovirus. J. Exp. Med.104, 289–304 (1956).

    PubMed  Google Scholar 

  15. Thomison, J. B.: Evolution of measles giant cells in tissue culture. Lab. Invest.11, 211–219 (1962).

    PubMed  Google Scholar 

Download references

Author information

Author notes

  1. Robert H. Bussell

    Present address: Department of Bacteriology, University of Kansas, Lawrence, Kansas, USA

Authors and Affiliations

  1. Department of Pathology Department of Pediatrics, Department of Bacteriology and Immunology, Medical School, State University of New York at Buffalo, Buffalo, New York

    Dorothy N. Shaver, Robert H. Bussell & Almen L. Barron

Authors
  1. Dorothy N. Shaver
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Robert H. Bussell
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Almen L. Barron
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Aided by Grant AI 04372-02 from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shaver, D.N., Bussell, R.H. & Barron, A.L. Comparative cytopathology of canine distemper and measles viruses in ferret kidney cell cultures. Archiv f Virusforschung 14, 487–498 (1964). https://doi.org/10.1007/BF01555080

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01555080

Keywords

Search

Navigation