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Dinamica degli acidi grassi non esterificati plasmatici (NEFA) nel dismetabolismo diabetogeno dell'eta' senile

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Riassunto

In 21 soggetti anziani non diabetici e in 21 soggetti anziani diabetici è stato esaminato il comportamento dei NEFA plasmatici durante l'iperglicemia da carico orale di glucosio (GTT), durante la prova del digiuno di 24 ore e dopo carico di carboidrati al termine del digiuno.

I due gruppi di soggetti dimostrano un diverso andamento della dinamica dei NEFA, il cui significato viene discusso.

Resume

On a étudié le comportement des NEFA plasmatiques en 21 sujets anciens non diabétiques et en 21 sujets anciens diabétiques, pendant l'hyperglycémie provoquée par charge orale de glucose (GTT), pendant l'essai du jeûne de 24 h et après charge de carbohydrates, une fois le jeûne achevé.

Les deux groupes de sujets montrent une différente allure de la dynamique des NEFA, dont on discute la signification.

Resumen

En 21 sujetos ancianos no diabeticos y en 21 sujetos ancianos diabeticos ha sido examinado el comportamiento de los NEFA plasmaticos durante la hiperglicemia de carga oral de glucosa (GTT), durante la prueba del ayuno de 24 h y déspues carga de carbohidratos al termino del ayuno.

Los grupos de sujetos demostran un diferente desarrollo de la dinamica de los NEFA, cuyo significado viene discutido.

Zusammenfassung

Bei 21 alten nicht Diabetikern und 21 alten Diabetikern wurde das Verhalten der plasmatischen NEFA waehrend einer Hyperglykaemie nach oraler Glukosebelastung (GTT), waehrend 24 stuendigem Fasten und Kohlehydratbelastung nach Beendigung des Fastens untersucht.

Die beiden Gruppen offenbaren ein unterschiedliches Verhalten der NEFA-Dynamik, dessen Bedeutung diskutiert wird.

Summary

In 21 non diabetic old subjects and in 21 diabetic old subjects the behaviour of plasma NEFA has been studied during hypoglycemia by glucose tolerance test, during 24-hours fasting test and after carbohydrates loading at the end of the fasting period.

A different dynamic behaviour of the NEFA levels has been found in the two groups. The results are discussed.

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Locatelli, G.R., Mazzi, C. & Piotti, L.E. Dinamica degli acidi grassi non esterificati plasmatici (NEFA) nel dismetabolismo diabetogeno dell'eta' senile. Acta diabet. lat 3, 51–60 (1966). https://doi.org/10.1007/BF01551351

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