Riassunto
Sono state eseguite prove convenzionali di tolleranza al glucosio orale in 100 maschi adulti giovani sistemicamente sani. Metà di questi soggetti sono stati classificati come relativamente esenti da complicazioni paradenziali (GPI = 1,60), mentre l'altra metà presentava manifestazioni di perdita di sostegno alveolare e, in generale, ha potuto essere classificata come bisognosa di trattamento paradenziale (GPI = 3,15). E' stata condotta un'analisi statistica allo scopo di rilevare differenze delle risposte al glucosio tra i due gruppi in tutti i tempi di prelievo, ma non è stato possibile riscontrare differenze significative.
Questi risultati confermano precedenti osservazioni del nostro laboratorio secondo le quali la determinazione della tolleranza al glucosio non può esprimere una predisposizione alle complicazioni del paradenzio in quest'età.
Resume
Les AA. ont exécuté destests de tolérance orale au glucose à 100 hommes jeunes adultes sains. La moitié de ces sujets ont été classifiés sans complications paradentales (GPI = 1,60), tandis que l'autre moitié présentait des manifestations de perte de soutien alvéolaire et, en géneral, a pu être classifié comme ayante besoin d'un traitement paradental (GPI = 3,15). Les AA. ont conduit aussi une analyse statistique à fin de relever les différentes reponses au glucose parmi les deux groupes dans tous les temps du prélèvement, mais il n'a pas été possible de noter des différences significatives.
Ces résultats confirment des observations précédentes du laboratoire selon lesquelles la détermination de la tolérance au glucose ne peut exprimer une prédisposition aux complications paradentales à cet âge.
Resumen
Han sido efectuado pruebas convencionales de tolerancia a la glucosa oral en 100 machos adultos jovenes sistemicamente sanos. Mitad de estos sujetos han sido clasificados como relativamente sin complicaciones paradentales (GPI = 1,60), mientras la otra mitad presentaba manifestaciones de perdida de sosten alveolar y, en general, ha podido ser clasificada como necesitada de tratamiento paradental (GPI = 3,15). Ha sido conducido un analisis estadistico al fin de relevar diferencias de las respuestas a la glucosa entre los dos grupos en todos los tiempos de toma, pero no ha sido posible encontrar diferencias significativas.
Estos resultados confirman precedentes observaciones de nuestro laboratorio, segun los cuales la determinacion de la tolerancia a la glucosa no puede expresar una tendencia a las complicaciones del paradencio en esta edad.
Zusammenfassung
Es wurden konventionelle orale Glukosetoleranzproben bei 100 systemisch gesunden jungen Erwachsenen durchgefuehrt. Die Haelfte dieser Personen wurde als relativ frei von paradentialen Komplikationen klassifiziert (GPI = 1,60); die andere Haelfte zeitige Aeusserungen eines Verlustes von alveolarem Stuetzgewebe und man konnte ganz allgemein die Notwendigkeit einer Paradentium-Behandlung feststellen (GPI = 3,15). Anlaesslich jeder Entnahmezeit wurde eine statistische Analyse durchgefuehrt, um Unterschiede in der Antwort beider Gruppen auf die Glukose festzustellen; man konnte jedoch keine signifikanten Unterschiede feststellen.
Diese Resultate bestaetigen vorherige Beobachtungen unseres Labors, laut welchen die Toleranz-Bestimmung gegenueber Glukose keine Praedisposition fuer Paradentium-Komplikationen in diesem Alter ausdruecken kann.
Summary
Conventional oral glucose tolerance tests were performed for 100 systemically healthy young adult males. Half of these subjects were classified as being relatively free of periodontal involvement (GPI = 1.60), while the other half presented evidence of loss of alveolar support and, in general, could be classified es requiring periodontal treatment (GPI = 3.15). Statistical analyses sought differences in glucose responses between the two groups at all sampling intervals. No significant differences were found.
These results confirm previous observations from this laboratory that glucose tolerance testing cannot be employed as an index of susceptibility to periodontal involvement in this age group.
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Shannon, I.L., O'Leary, T.J., Gibson, W.A. et al. Oral glucose tolerance and periodontal status. Acta diabet. lat 3, 33–45 (1966). https://doi.org/10.1007/BF01551349
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DOI: https://doi.org/10.1007/BF01551349