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Effects of nutrients on gastrointestinal motility and gastric emptying after Billroth-I gastrectomy in dogs

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Abstract

We wanted to clarify the way in which nutrients influence gastrointestinal motility and gastric emptying following distal gastrectomy with Billroth-I gastroduodenostomy. Four gastrectomized dogs were equipped with extraluminal strain gauge transducers. Gastric emptying was measured radiographically. Four intact dogs were used as controls for emptying studies. Following gastrectomy, gastric emptying of both acaloric and nutrient meals was rapid in the initial period of the experiments. Gastric outflow was supported by propagating duodenal contractions. Compared with control dogs, the early emptying of nutrient meals was accelerated. In the following period, nutrients markedly slowed gastric emptying compared with acaloric meals due to a segmenting contractile pattern of the duodenum and a significant diminution of gastrointestinal motility. Results suggest that after Billroth-I gastrectomy (1) the control of gastric emptying by nutrients acts too late to slow the initial enhanced gastric outflow, and (2) the duodenal contractile patterns influence gastric emptying.

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Authors and Affiliations

  1. Institut für Zoophysiologie, Universität Hohenheim, Garbenstr. 30, D-7000, Stuttgart 70, F.R.G.

    Sabine Bühner, Hans-Jörg Ehrlein, Gert Thoma & Volker Schumpelick

  2. Department of Surgery, University of Hamburg, F.R.G.

    Sabine Bühner, Hans-Jörg Ehrlein, Gert Thoma & Volker Schumpelick

Authors
  1. Sabine Bühner
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  2. Hans-Jörg Ehrlein
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  3. Gert Thoma
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  4. Volker Schumpelick
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Additional information

The study was supported by the Deutsche Forschungsgemeinschaft, grant Eh 64/3-1.

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Bühner, S., Ehrlein, HJ., Thoma, G. et al. Effects of nutrients on gastrointestinal motility and gastric emptying after Billroth-I gastrectomy in dogs. Digest Dis Sci 33, 784–794 (1988). https://doi.org/10.1007/BF01550964

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  • DOI: https://doi.org/10.1007/BF01550964

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