The herbicide, 2,4-Dichlorophenoxyacetic acid, 2-ethyl hexyl ester (Weed RhapR), produced a decrease in plasma calcium and increase in plasma magnesium, giving a significant ratio change in the plasma of the 2 sheep and yearling heifer that died. Each of these had increased blood urea nitrogen (BUN) levels, and the pathological examinations at necropsy showed kidney damage and swollen, blood-engorged thyroids. The formulation of the dose in sheep either as emulsifiable concentrate (EC) or as technical material, showed no effect difference.
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Hunt, L.M., Gilbert, B.N. & Palmer, J.S. Effects of a herbicide, 2-ethyl hexyl ester of 2,4-D on magnesium: Calcium ratios and blood urea nitrogen levels in sheep and cattle. Bull. Environ. Contam. Toxicol. 5, 54–60 (1970). https://doi.org/10.1007/BF01545126
- Pathological Examination
- Blood Urea Nitrogen
- Nitrogen Level