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Protein synthesis by rat hepatoma × mouse teratocarcinoma somatic cell hybrids

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Somatic Cell Genetics

Abstract

The synthesis of intracellular and secretory proteins by rat hepatoma (MHC) and mouse teratocarcinoma (PCC4AZA1) cells and MHC x PCC4AZA1 somatic cell hybrids was examined with two-dimensional (O'Farrell) electrophoresis. The gels of the PCC4AZA1 and hybrid cells were nearly identical and were quite different from those of the MHC cells. The teratocarcinoma phenotype was, therefore, dominant in the teratocarcinoma x hepatoma somatic cell hybrids.

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Author notes

  1. L. K. Wray

    Present address: Department of Human Genetics, University of Pennsylvania, School of Medicine, 19104, Philadelphia, Pennsylvania

  2. H. K. Jaeckle

    Present address: Abteilung Biochemie, Max-Planck-Institut Fur Virusforschung, Spemannstrasse 35/II, T4 Tubingen, FRG

Authors and Affiliations

  1. Department of Zoology, and The Genetics Institute, The University of Texas at Austin, 78712, Austin, Texas

    L. K. Wray & H. K. Jaeckle

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  1. L. K. Wray
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  2. H. K. Jaeckle
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Wray, L.K., Jaeckle, H.K. Protein synthesis by rat hepatoma × mouse teratocarcinoma somatic cell hybrids. Somat Cell Mol Genet 9, 111–119 (1983). https://doi.org/10.1007/BF01544052

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  • DOI: https://doi.org/10.1007/BF01544052

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