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Modulation of esophageal peristalsis by alterations of body position

Effect of bolus viscosity

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Abstract

Previous studies have demonstrated that nonviscous liquids traverse the esophagus more rapidly with the subject in the upright rather than the supine position. Conversely, similar studies have shown that viscous liquids traverse the esophagus at similar rates for both upright and supine positions. Our purpose was to define the motor correlates of these differing responses. Six normal volunteers were studied with an infused catheter system incorpoating a Dent sleeve for monitoring lower esophageal sphincter pressure. The subjects were given a series of swallows of a water and a viscous (52 centipoise) bolus in both the supine and upright positions. In the upright position, the water bolus caused an increased velocity of propagation in the proximal esophageal segment that was associated with a shortening of lower esophageal sphincter relaxation time and reductions in amplitude and duration of contraction. No significant changes in the peristaltic wave were noted with the viscous bolus during alterations of body position. We conclude that the more rapid transit of a nonviscous water bolus through the esophagus in the upright position is reflected in specific alterations of esophageal peristaltic parameters. The possible mechanisms for these differing responses are discussed.

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References

  1. Meyer GW, Gerhardt DC, Castell DO: Human esophageal response to rapid swallowing: Muscle refractory period or neural inhibition? Am J Physiol 241:G129-G136, 1981

    PubMed  Google Scholar 

  2. Vaneck AW, Diamant NE: Responses of the human esophagus to paired swallows. Gastroenterology 92:643–650, 1987

    Google Scholar 

  3. Mellow MH: Esophageal motility during food ingestion: A physiologic test of esophageal motor function. Gastroenterology 85:570–577, 1983

    Google Scholar 

  4. Dodds WJ, Hogan WJ, Stewart ET, Stef JT, Arndorfer RC: Effects of increased intraabdominal pressure on esophageal peristalsis. J Appl Physiol 37:378–383, 1974

    PubMed  Google Scholar 

  5. Hollis JB, Castell DO: Effect of dry swallows and wet swallows of different volumes on esophageal peristalsis. J Appl Physiol 38:1161–1164, 1975

    PubMed  Google Scholar 

  6. Kaye MD, Kilby AE, Harper PC: Changes in distal esophageal function in response to cooling. Dig Dis Sci 32:22–27, 1987

    PubMed  Google Scholar 

  7. Winship DH, Viegas De Andrade SR, Zboralske FF: Influence of bolus temperature on human esophageal motor function. J Clin Invest 49:243–250, 1970

    PubMed  Google Scholar 

  8. Cannon WB, Moser A: The movements of food in the esophagus. Am J Physiol 1:435–444, 1898

    Google Scholar 

  9. Palugyay J. Roentgenstudien ueber den oesophagealen schluckakt. Ein beitrag zur speisroerhenphysiologie. Pfluegers Arch Gesamte Physiol Menschen Tiere 200:620–641, 1923

    Google Scholar 

  10. Ingelfinger FJ: Esophageal motility. Physiol Rev 38:533–584, 1958

    PubMed  Google Scholar 

  11. Dooley CP, Schlossmacher B, Valenzuela JE: Effects of alterations in bolus viscosity on esophageal peristalsis in humans. Am J Physiol 254:G8-G11, 1988

    PubMed  Google Scholar 

  12. Kahrilas PJ, Dodds WJ, Hogan WJ, Kern M, Arndorfer RC, Reece A: Esophageal peristaltic dysfunction in peptic esophatitis. Gastroenterology 91:897–904, 1986

    PubMed  Google Scholar 

  13. Kaye MD, Wexler RM: Alteration of esophageal peristalsis by body position. Dig Dis Sci 26:897–901, 1981

    PubMed  Google Scholar 

  14. Buthpitiya AG, Stroud D, Russell COH: Pharyngeal pump and esophageal transit. Dig Dis Sci 32:1244–1248, 1987

    PubMed  Google Scholar 

  15. Cohen S, Green F: The mechanics of esophageal muscle contraction. Evidence of an inotropic effect of gastrin. J Clin Invest 52:2029–2040, 1973

    PubMed  Google Scholar 

  16. Winship DH, Zboralske FF: The esophageal propulsive force: response to obstruction. J Clin Invest 46:1391–1401, 1967

    PubMed  Google Scholar 

Download references

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Dooley, C.P., Schlossmacher, B. & Valenzuela, J.E. Modulation of esophageal peristalsis by alterations of body position. Digest Dis Sci 34, 1662–1667 (1989). https://doi.org/10.1007/BF01540041

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  • DOI: https://doi.org/10.1007/BF01540041

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