Abstract
Significant changes occurred in the rate of synthesis of several polypeptides in two different Drosophilacell lines following exposure to the steroid hormone, β-ecdysone. For peptide 7/8, the synthetic rate increased by a factor of 10 in line S3 and by a factor of 1.3 in line MDR. In hormone-sensitive hybrids the rate increased by a factor of 3–4.5. For peptide 10 the synthetic rate decreased by a factor of 8 in line S3 but increased by a factor of 2 in line MDR. In hormone-sensitive hybrids the synthetic rate increased by a factor of 2–3. In hormone-insensitive cell lines no change in the rate of peptide synthesis occurred in the presence of hormone.
Similar content being viewed by others
Literature cited
Gehring, U., and Thompson, E.B. (1979). In:Glucocorticoid Hormone Action, (ed.) Baxter, J.D., and Rousseau, G.G. (Springer-Verlag, Berlin), p. 399.
Courgeon, A.M. (1972).Exp. Cell Res. 74:327.
Cherbas, P., Cherbas, L., and Williams, C.M. (1977).Science 197:275.
Berger, E., Ringler, R., and Alahiotis, S. (1978).Dev. Biol. 62:498.
Best-Belpomme, M., and Courgeon, A.M. (1977).FEBS Lett. 82:345.
Best-Belpomme, M., Corgeon, A.M., and Rambach, A. (1978).Proc. Natl. Acad. Sci. U.S.A. 75:6102.
Wyss, C., and Eppenberger, H.M. (1978).Experientia 34:961.
Wyss, C. (1979).Somat. Cell Genet. 5:29.
Wyss, C. (1980).Exp. Cell Res. 125:121.
Maroy, P., Dennis, R., Beckers, C., Sage, B., and O'Conner, J. (1978).Proc. Natl. Acad. Sci. U.S.A. 75:6035.
Yund, M.A., King, D., and Fristrom, J.W. (1978).Proc. Natl. Acad. Sci. U.S.A. 75:6035.
Schneider, I. (1972).J. Embryol. Exp. Morphol. 27:353.
Shields, G., and Sang, J.H. (1977).Drosophila Information Service 52:161.
Alahiotis, S., and Berger, E. (1977).Biochem. Genet. 15:877.
O'Farrell, P.H. (1975).J. Biol. Chem. 25:4007.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Berger, E., Ireland, R. & Wyss, C. Pattern of peptide synthesis inDrosophila cell lines and their hybrids. Somat Cell Mol Genet 6, 719–729 (1980). https://doi.org/10.1007/BF01538971
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF01538971