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Biological interventions in psychoses of childhood

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Abstract

An up-to-date review of biological interventions in phychoses of childhood is presented together with occasional comments on efficacy based on the author's experience. After brief mention of earlier forms of biological-organic treatment (psychosurgery, insulin, and electroconvulsive therapies), the review focuses on drug therapy. Relative prominence is given to major tranquilizers, lithium, and the hormones. Suitable information is also presented on hypnotics, anticonvulsants, sedatives, stimulants, antidepressant drugs, minor tranquilizers, hallucinogens, L-dopa, and vitamins. It is suggested that no specific drug is available for the treatment of any diagnostic category. Currently available drugs are most effective in reducing such symptoms as insomnia, hyperactivity, impulsivity, irritability, disorganized behavior, psychotic thought disorder, and certain type of aggressivity. The need for uniformity in the classification of child psychoses is stressed in light of its potential value in predicting responses of children to specific drugs.

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Paper to be read on November 1, 1973 at the First International Leo Kanner Colloquium on Child Development, Deviations and Treatment, Chapel Hill, N.C. Part of the work was supported by Public Health Service Grant MH-04665 from the National Institute of Mental Health. The author wishes to thank Mrs. Loren Wissner Greene for her assistance in the literature search.

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Campbell, M. Biological interventions in psychoses of childhood. J Autism Dev Disord 3, 347–373 (1973). https://doi.org/10.1007/BF01538542

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