The purpose of this investigation was to compare the effect of body posture on gastric emptying measurements of radiolabeled meals. Eight healthy male subjects were studied on four separate days. During each study subjects were fed a standardized meal of beef stew labeled with technetium-99m sulfur colloid, and orange juice. Measurements of solid-phase gastric emptying rates were obtained by a gamma camera. Subjects were studied in the lying, sitting, standing, or combined sitting-standing postures. The results demonstrated that the lying position significantly slowed gastric emptying compared to all other positions. Conversely, a decrease in emptying times of 51% and 35% occurred in the combined sitting-standing position compared to the lying and sitting position. These results support a marked effect of body posture on the radionuclide measurement of gastric emptying.
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Griffith GH, Owen GM, Kirkman S, Shields R: Measurement of the rate of gastric emptying using chromium-51. Lancet 1:1244–1245, 1966
Heading RC, Tothill P, McGloughlin GP, Shearman DJC: Gastric emptying rate measurement in man. A double isotope scanning technique for simultaneous study of liquid and solid components of a meal. Gastroenterology 71:45–50, 1976
Meyer JH, MacGregor IL, Guellar R, Martin P, Cavalieri R:99mTc-tagged chicken liver as a marker of solid food in the human stomach. Am J Dig Dis 21:296–304, 1976
Moore JG, Christian PE, Coleman RE: Gastric emptying of varying meal weight and composition in man. Evaluation by dual liquid and solid-phase isotopic method. Dig Dis Sci 26(1):16–22, 1981
McCallum RW, Berkowitz DM, Lerner E: Gastric emptying in patients with gastroesophageal reflux. Gastroenterology 80:285–291, 1981
Loo FD, Palmer DW, Soergel KH, Kalbfleisch JH, Wood CN: Gastric emptying in patients with diabetes mellitus. Gastroenterology 86:485–494, 1984
Jian R, Vigneron N, Najean Y, Bernier J: Gastric emptying and intragastric distribution of lipids in man. A new scintigraphic method of study. Dig Dis Sci 27(8):705–711, 1982
Cammack J, Read NW, Cann PA, Greenwood B, Holgate AM: Effect of prolonged exercise on the passage of a solid meal through the stomach and small intestine. Gut 23:957–961, 1982
Dugas MC, Schade RR, Lhotsky D, VanThiel D: Comparison of methods for gastric isotope emptying. Am J Physiol 243(3):6237–6242, 1982
Wright RA, Krinsky S, Fleeman C, Trujillo J, Teague E: Gastric emptying and obesity. Gastroenterology 84:747–751, 1983
Collins PJ, Horowitz M, Cook DJ, Harding PE, Shearman DJC: Gastric emptying in normal subjects-a reproducible technique using a single scintillation camera and computer system. Gut 24:1117–1125, 1983
Christian PE, Moore JG, Datz FL: Comparison of Tc-99m-labelled liver and liver paté as markers for solid phase gastric emptying. J Nucl Med 25:364–366, 1984
Siegel JA, Wu RK, Knight LC, Zelec RE, Stern HS, Malmud LS: Radiation dose estimates for oral agents used in gastrointestinal disease. J Nucl Med 24:835–837, 1983
Moore JG, Christian PE, Taylor AT, Alazaraki N: Gastric emptying measurements: Delayed and complex patterns without appropriate correction. J Nucl Med 26:1206–1210, 1985
Tothill P, McLoughlin GP, Holt S, Heading RC: The effect of posture on errors in gastric emptying measurements. Phys Med Biol 25(6):1071–1077, 1980
Datz FL, Christian PE, Moore JG, Thome DA: Sex-related differences in gastric emptying. J Nucl Med 28:1204–1207, 1987
Goo RH, Moore JG, Greenberg E, Alazaraki N: Circadian variation in gastric emptying of meals in man. Gastroenterology 93:515–518, 1987
Tothill P, McLoughlin GP, Heading RC: Technique and errors in scintigraphic measurements of gastric emptying. J Nucl Med 19:256–261, 1978
Malmud LS, Fisher RS, Knight LC, Rock E: Scintigraphic evaluation of gastric emptying. Semin Nucl Med 12:116–125, 1982
Meyer JH, VanDeventer G, Graham LS, et al: Error and corrections with scintigraphic measurements of gastric emptying of solid foods. J Nucl Med 24:197–203, 1983
Mojaverian P, Vlasses PH, Clement RA, Rocci ML: The effect of gender and posture on the gastric residence time of an indigestible solid in man. Gastroenterology 90:1556, 1986 (abstract)
Mojaverian P, Rocci ML, Conner DP, Abrams WB, Vlasses PH: Effect of food on the absorption of enteric-coated aspirin: Correlation with gastric residence time. Clin Pharmacol Ther 41:11–17, 1987
The authors wish to acknowledge the Salt Lake City Veterans Administration Medical Center, Department of Research for support of this work.
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Moore, J.G., Datz, F.L., Christian, P.E. et al. Effect of body posture on radionuclide measurements of gastric emptying. Digest Dis Sci 33, 1592–1595 (1988). https://doi.org/10.1007/BF01535951
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