Digestive Diseases and Sciences

, Volume 33, Issue 2, pp 129–134 | Cite as

GSRS—A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease

  • Jan Svedlund
  • Ingemar Sjödin
  • Gerhard Dotevall
Original Articles


An interview-based rating scale consisting of 15 items for assessment of gastrointestinal symptoms in irritable bowel syndrome and peptic ulcer disease has been developed. The interrater reliability was estimated by means of independent and simultaneous duplicate ratings by two raters in 20 cases and ranged from 0.86 to 1.00. The scale was easy to apply and proved to be useful in comparing the effectiveness of different modes of treatment in two clinical trials.

Key words

symptom rating clinical assessment treatment evaluation irritable bowel syndrome peptic ulcer disease 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Svedlund J, Sjödin I, Dotevall G, Gillberg R: Upper gastrointestinal and mental symptoms in the irritable bowel syndrome. Scand J Gastroenterol 20:595–601, 1985PubMedGoogle Scholar
  2. 2.
    Sjödin I, Svedlund J, Dotevall G, Gillberg R: Symptom profiles in chronic peptic ulcer disease. Scand J Gastroenterol 20:419–427, 1985PubMedGoogle Scholar
  3. 3.
    Feinstein AR: An additional basic science for clinical medicine: IV: The development of clinimetrics. Ann Intern Med 99:843–848, 1983PubMedGoogle Scholar
  4. 4.
    Fletcher RH, Fletcher SW: Clinical research in general medical journals. N Engl J Med 301:180–183, 1979PubMedGoogle Scholar
  5. 5.
    Snape WJ Jr, Carlson GM, Cohen S: Colonic myoelectric activity in the irritable bowel syndrome. Gastroenterology 70:326–330, 1976PubMedGoogle Scholar
  6. 6.
    Snape WJ Jr, Carlson GM, Matarazzo SA, Cohen S: Evidence that abnormal myoelectrical activity produces colonic motor dysfunction in the irritable bowel syndrome. Gastroenterology 72:383–387, 1977PubMedGoogle Scholar
  7. 7.
    Taylor I, Darby C, Hammond P, Basu P: Is there a myoelectrical abnormality in the irritable colon syndrome? Gut 19:391–395, 1978PubMedGoogle Scholar
  8. 8.
    Latimer PR: Behavioral assessment.In Functional Gastrointestinal Disorders. A Behavioral Medicine Approach. New York, Springer, 1983, pp. 83–106Google Scholar
  9. 9.
    Bates S, Sjödén P-O: Registration of pain in a psychological perspective. Scand J Gastroenterol 20(suppl 109):15–18, 1985Google Scholar
  10. 10.
    Montgomery SA, Åsberg M: A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382–398, 1979PubMedGoogle Scholar
  11. 11.
    Montgomery SA, Taylor P, Montgomery D: Development of a schizophrenia scale sensitive to change. Neuropsychopharmacology 17:1061–1063, 1978Google Scholar
  12. 12.
    Mindus P, Struwe G, Gullberg B: A CPRS subscale to assess mental symptoms in workers exposed to jet fuel-some methodological considerations. Acta Psychiatr Scand Suppl 271:53–62, 1978PubMedGoogle Scholar
  13. 13.
    Thorén P, Åsberg M, Cronholm B, Jörnestedt L, Träskman L: Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial. Arch Gen Psychiatry 37:1281–1285, 1980PubMedGoogle Scholar
  14. 14.
    Svedlund J, Sjödin I, Ottosson J-O, Dotevall G: Controlled study of psychotherapy in irritable bowel syndrome. Lancet 2:589–592, 1983PubMedGoogle Scholar
  15. 15.
    Sjödin I, Svedlund J, Ottosson J-O, Dotevall G: Controlled study of psychotherapy in chronic peptic ulcer disease. Psychosomatics 27:187–200, 1986PubMedGoogle Scholar
  16. 16.
    Åsberg M, Perris C, Schalling D, Sedvall G: The CPRS-development and applications of a psychiatric rating scale. Acta Psychiatr Scand Suppl 271:5–27, 1978PubMedGoogle Scholar
  17. 17.
    Kramer MS, Feinstein AR: Clinical biostatistics: LIV: The biostatistics of concordance. Clin Pharmacol Ther 29:111–123, 1981PubMedGoogle Scholar
  18. 18.
    Manning AP, Thompson WG, Heaton KW, Morris AF: Towards positive diagnosis of the irritable bowel. Br Med J 2:653–654, 1978PubMedGoogle Scholar
  19. 19.
    Kruis W, Thieme CH, Weinzierl M, Schüssler P, Holl J, Paulus W: A diagnostic score for the irritable bowel syndrome. Its value in the exclusion of organic disease. Gastroenterology 87:1–7, 1984PubMedGoogle Scholar
  20. 20.
    Thompson WG: Gastrointestinal symptoms in the irritable bowel compared with peptic ulcer and inflammatory bowel disease. Gut 25:1089–1092, 1984PubMedGoogle Scholar
  21. 21.
    Thompson WG, Heaton KW: Functional bowel disorders in apparently healthy people. Gastroenterology 79:283–288, 1980PubMedGoogle Scholar
  22. 22.
    Drossman DA, Sandler RS, McKee DC, Lovitz AJ: Bowel patterns among subjects not seeking health care. Use of a questionnaire to identify a population with bowel dysfunction. Gastroenterology 83:529–534, 1982PubMedGoogle Scholar
  23. 23.
    Whitehead WE, Winget C, Fedoravicius AS, Wooley S, Blackwell B: Learned illness behavior in patients with irritable bowel syndrome and peptic ulcer. Dig Dis Sci 27:202–208, 1982PubMedGoogle Scholar
  24. 24.
    Sandler RS, Drossman DA, Nathan HP, McKee DC: Symptom complaints and health care seeking behavior in subjects with bowel dysfunction. Gastroenterology 87:314–318, 1984PubMedGoogle Scholar
  25. 25.
    Sjödén P-O, Bates S, Nyrén O: Continuous self-recording of epigastric pain with two rating scales: Compliance, authenticity, reliability, and sensitivity. J Behav Assess 5:327–344, 1983Google Scholar
  26. 26.
    Nyrén O, Adami HO, Bates S, Bergström R, Gustavsson S, Lööf L, Nyberg A: Absence of therapeutic benefit from antacids or cimetidine in nonulcer dyspepsia. N Engl J Med 314:339–343, 1986PubMedGoogle Scholar
  27. 27.
    Saunders JHB, Oliver RJ, Higson DL: Dyspepsia: Incidence of nonulcer disease in a controlled trial of ranitidine in general practice. Br Med J 292:665–668, 1986Google Scholar
  28. 28.
    Sacket DL: On some prerequisites for a successful clinical trial.In Clinical Trials. Issues and Approaches. SH Shapiro, TA Louis (eds). New York, Marcel Dekker, 1983, pp 65–79Google Scholar
  29. 29.
    Adami HO: The role and conduct of clinical trials in the treatment of peptic ulcer disease.In Pharmacological Treatment of Ulcer and Nonulcer Dyspepsia. National Board of Health and Welfare Drug Information Committee, Sweden, 1985, No. 3, pp 35–47Google Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Jan Svedlund
    • 1
    • 2
  • Ingemar Sjödin
    • 1
    • 2
  • Gerhard Dotevall
    • 1
    • 2
  1. 1.Department of Psychiatry, and Division of Gastroenterology, Medical Department II, Sahlgren HospitalUniversity of Göteborg45 GöteborgSweden
  2. 2.Department of Psychiatry, Region HospitalUniversity of Linköping85 LinköpingSweden

Personalised recommendations