Advertisement

Somatic Cell and Molecular Genetics

, Volume 15, Issue 3, pp 265–270 | Cite as

The gene for prolactin-inducible protein (PIP), uniquely expressed in exocrine organs, maps to chromosome 7

  • Yvonne Myal
  • Carolyn Gregory
  • Hui Wang
  • John L. Hamerton
  • Robert P. C. Shiu
Brief Communication

Abstract

The hormonally responsive prolactin-inducible protein (PIP), gene is expressed in benign and malignant breast tumor tissues and in such normal exocrine organs as sweat, salivary, and lacrimal glands. In this communication we report the regional chromosome localization of the PIPgene locus to chromosome 7 by Southern hybridization to DNA from human-hamster somatic cell hybrids, and to 7q32–36 by in situ hybridization.

Keywords

Tumor Tissue Somatic Cell Breast Tumor Regional Chromosome Chromosome Localization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    Welsch, C.W., and Nagasawa, H. (1977).Cancer Res. 37:951–963.PubMedGoogle Scholar
  2. 2.
    Shiu, R.P.C., and Iwasiow, B.M. (1985).J. Biol. Chem. 260:11307–11313.PubMedGoogle Scholar
  3. 3.
    Murphy, L.C., Tsuyuki, D., Myal, Y., and Shiu, R.P.C. (1987).J. Biol. Chem. 262:15236–15341.PubMedGoogle Scholar
  4. 4.
    Murphy, L.C., Lee-Wing, M., Goldenberg, G.J., and Shiu, R.P.C. (1987).Cancer Res 47:4160–4164.PubMedGoogle Scholar
  5. 5.
    Haagensen, D.E., Jr., and Mazoujian, G. (1986). InDiseases of the Breast, 3rd ed., (ed.) Haagenson, C.D. (W.B. Saunders, Philadelphia), pp. 474–500.Google Scholar
  6. 6.
    Riddell, D.C., Mallonee, R., Phillips, J.A., Parks, J.S., Sexton, L.A., and Hamerton, J.L. (1985).Somat. Cell Mol. Genet. 2:189–195.Google Scholar
  7. 7.
    Royle, N.J., Fung, M.R., MacGillavary, R.J.A., and Hamerton, J.L. (1986).Cytogenet Cell. Genet. 41:185–188.PubMedGoogle Scholar
  8. 8.
    Maniatis, T., Kee, S.G., Efsradiatis, A., and Kafatos, F.C. (1976).Cell 27:583–591.Google Scholar
  9. 9.
    Lin, C.C., Draper, P.N., and De Brackeleer, M. (1985).Cytogenet. Cell Genet. 39:269–274.PubMedGoogle Scholar
  10. 10.
    Arrand, J. (1985). InNucleic Acid Hybridization: A Practical Approach, 3rd ed., (eds.) Hames, B.D., and Higgins, S.J. (IRL Press, Washington, D.C.), pp. 21–22.Google Scholar
  11. 11.
    Reed, K.C., and Mann, D.A. (1985).Nucleic Acids Res. 13:7207–7221.PubMedGoogle Scholar
  12. 12.
    Wang, H., Riddell, D.C., Guinto, E.R., MacGillivary, R.T.A., and Hamerton, J.L. (1988).Genomics 2:324–328.PubMedGoogle Scholar
  13. 13.
    Harper, M.A., and Saunders, G.T. (1981).Chromosoma 83:431–439.PubMedGoogle Scholar
  14. 14.
    Robertson, M., Boyajian, M., Patterson, K., and Robertson, W.V.B. (1986).Endocrinology 119:2439–2443.PubMedGoogle Scholar
  15. 15.
    Beaudet, A., Bowcock, A., Buchwald, M., Cavalli, P., Sforza, L., Farral, M., King, M.C., Klinger, K., Lalouel, J.M., Lathrop, G., Naylor, S., Ott, J., Tsui, L., Watkins, P., White, R., and Williamson, R., (1986).Am. J. Hum. Genet. 39:681–693.PubMedGoogle Scholar
  16. 16.
    Quinton, P.M. (1983).Nature 301:421–422.PubMedGoogle Scholar
  17. 17.
    Knowles, M.R., Gatzy, J.T., and Boucher, R.C. (1983).J. Clin. Invest. 71:1410–1417.PubMedGoogle Scholar
  18. 18.
    Bell, D.R., Trent, J.M., Willard, H.F., Riodan, J.R., and Ling, V. (1987).Cancer Genet. Cytogenet 25:141–148.PubMedGoogle Scholar
  19. 19.
    Fairchild, C.R., Ivy, S.P., Kao-Shan, C.S., Whang-Peng, J., Rosen, N., Israel, M.A., Melera, P.W., Cowan, K.H., and Goldsmith, M.E. (1987).Cancer Res. 47:5141–5148.PubMedGoogle Scholar
  20. 20.
    Berger, R., Bloomfield, C.D., and Sutherland, G.R. (1985).Cytogenet. Cell Genet. 40:490–535.PubMedGoogle Scholar
  21. 21.
    Yunis, J.J., Soreng, A.L., and Bowe, A.E. (1987).Oncogene 1:59–69.PubMedGoogle Scholar
  22. 22.
    Le Beau, M.M. (1986).Blood 67:849–858.PubMedGoogle Scholar
  23. 23.
    Yunis, J.J., and Soreng, A.L. (1984).Science 226:1199–1204.PubMedGoogle Scholar
  24. 24.
    De Braekeleer, M., Smith, B., and Lin, C.C. (1985).Hum. Genet. 69:112–116.PubMedGoogle Scholar
  25. 25.
    Gebhart, E., Bruderlein, S., Augustus, M., Siebert, E., Feldner, J., and Schmidt, W. (1986).Treatment Res. 8:125–138.Google Scholar
  26. 26.
    Rodgers, C.S., Hill, S.M., and Hulten, M.A. (1984).Cancer Genet. Cytogenet 13:95–119.PubMedGoogle Scholar
  27. 27.
    Wong, Z., Wilson, V., Patel, I., Povey, S., and Jeffreys, A.J. (1987).Ann. Hum. Genet. 51:269–288.PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Yvonne Myal
    • 1
  • Carolyn Gregory
    • 2
  • Hui Wang
    • 2
  • John L. Hamerton
    • 2
  • Robert P. C. Shiu
    • 1
  1. 1.Department of Physiology, Faculty of MedicineUniversity of ManitobaWinnipegCanada
  2. 2.Department of Human Genetics, Faculty of MedicineUniversity of ManitobaWinnipegCanada

Personalised recommendations