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The location of the gene for haemophilia

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Summary

Sirks' theory that the gene for haemophilia can cross over between the X and Y chromosomes is critically examined. The cross-over frequency must be of the order of one in ten thousand. Some difficulties in the theory are pointed out, and methods by which it may be tested are discussed.

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Haldane, J.B.S. The location of the gene for haemophilia. Genetica 20, 423–430 (1938). https://doi.org/10.1007/BF01531776

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  • DOI: https://doi.org/10.1007/BF01531776

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