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Membrane fusion in the rod outer segment disk membrane

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Abstract

The rod outer segment disk membrane of bovine retina has been isolated in a predominantly fused state. The physical and chemical properties of the membrane in the fused state are profoundly different from the corresponding properties of the same membrane in the unfused state. Exposure to light induces the transition of the disk membrane from the fused to the unfused state. Evidence is presented which suggests that the fusion-defusion cycle of the disk membrane is a primary event of photoexcitation and nerve stimulation.

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References

  1. M. M. Dewey, P. K. Davis, J. K. Blasie and L. Barr,J. Mol. Biol.,39 (1969) 395.

    PubMed  Google Scholar 

  2. J. K. Blasie, C. R. Worthington and M. M. Dewey,J. Mol. Biol.,39 (1969) 407.

    PubMed  Google Scholar 

  3. H. Fernandez-Moran in:The Structure of the Eye (G. K. Smelsen, ed.), Academic Press (1961) 521.

  4. A. E. Blaurock and M. H. F. Wilkins,Nature,237 (1972) 313.

    Google Scholar 

  5. J. M. Corless,Nature,237 (1972) 229.

    Google Scholar 

  6. C. C. Ramsen, F. W. Valois and S. W. Watson,J. Bacteriol. 94 (1967) 422.

    PubMed  Google Scholar 

  7. R. A. Dilley, D. W. Krogman, S. Berg and S. Dodge,Plant Physiology, Suppl. 4a, (1972) 27.

    Google Scholar 

  8. U. W. Goodenough, and L. A. Staehelin,J. Cell. Biol. 48 (1971) 594.

    Google Scholar 

  9. J. D. Robertson, in:Handbook of Molecular Cytology (A. Lima-de-Faria, ed.), North-Holland, Amsterdam, (1969) Chapter 52, 1404.

    Google Scholar 

  10. G. Vanderkooi and M. Sundaralingam,Proc. Nat. Acad. Sci. U.S.A.,67 (1970) 233.

    Google Scholar 

  11. C. R. Worthington,Fed. Proc.,30, (1971) 57.

    PubMed  Google Scholar 

  12. A. E. Blaurock and M. H. F. Wilkins,Nature,223 (1969) 906.

    PubMed  Google Scholar 

  13. J. K. Blasie,Biophysical J. 12 (1972) 191.

    Google Scholar 

  14. E. A. Dratz, J. E. Gaw, S. Schwartz and W. Ching,Nature New Biology,237 (1972) 99.

    PubMed  Google Scholar 

  15. S. Murakami and L. Packer,Arch. Biochem. Biophys.,146 (1971) 337.

    PubMed  Google Scholar 

  16. D. E. Green,Ann. N.Y. Acad. Sci.,195 (1972) 150.

    PubMed  Google Scholar 

  17. D. W. Deamer, A. R. Crofts and L. Packer,Biochim. Biophys. Acta,131 (1967) 81.

    Google Scholar 

  18. M. Chabre and A. Cavaggioni,Nature New Biology,244 (1973) 118.

    PubMed  Google Scholar 

  19. P. K. Brown,Nature New Biology,236 (1972) 35.

    PubMed  Google Scholar 

  20. K. Hong and W. L. Hubbell,Proc. Nat. Acad. Sci. U.S.A.,69 (1972) 2617.

    Google Scholar 

  21. F. D. Collins, R. M. Love and R. A. Morton,Biochem. J.,51 (1952) 669.

    PubMed  Google Scholar 

  22. S. Fleischer and D. G. McConnell,Nature,212 (1966) 1366.

    PubMed  Google Scholar 

  23. C. W. Wu and L. Stryer,Proc. Nat. Acad. Sci. U.S.A.,69 (1972) 1104.

    Google Scholar 

  24. H. Heitzman and F. M. Richards,Biophys. Soc. Abst. (1973).

  25. R. A. Cone,Nature New Biology,236 (1972) 39.

    PubMed  Google Scholar 

  26. D. Oesterhelt and W. Stoeckenius,Proc. Nat. Acad. Sci. U.S.A.,70 (1973) 2853.

    Google Scholar 

  27. E. Racker,Biochem. Biophys. Res Commun.,55 (1973), 224.

    PubMed  Google Scholar 

  28. A. L. Shapiro, E. Vinuela and J. V. Maizel,Biochem. Biophys. Res. Commun.,28 (1967) 815.

    PubMed  Google Scholar 

  29. A. G. Gornall, C. J. Bardawill and M. M., David,J. Biol. Chem.,177 (1949) 751.

    Google Scholar 

  30. O. H. Lowry, N. J. Rosenbough, A. L. Farr and R. J. Randall,J. Biol. Chem.,193 (1951) 265.

    PubMed  Google Scholar 

  31. P. S. Chan, T. Y. Troibara and H. Warner,Anal. Chem.,28 (1956) 1756.

    Google Scholar 

  32. T. Wakabayashi, E. F. Korman and D. E. Green,Bioenergetics,2 (1971) 233.

    Google Scholar 

  33. W. T. Mason, R. S. Fager and E. W. Abrahamson,Nature,247 (1974) 562.

    PubMed  Google Scholar 

  34. P. K. Brown and G. Wald,J. Biol. Chem. 222 (1956) 865.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Institute for Enzyme Research, University of Wisconsin, 53706, Madison, Wisconsin

    Ralph J. Kessler, Takashi Wakabayashi & David E. Green

Authors
  1. Ralph J. Kessler
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  2. Takashi Wakabayashi
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  3. David E. Green
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Kessler, R.J., Wakabayashi, T. & Green, D.E. Membrane fusion in the rod outer segment disk membrane. J Bioenerg Biomembr 6, 205–220 (1974). https://doi.org/10.1007/BF01520862

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  • DOI: https://doi.org/10.1007/BF01520862

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