Abstract
In-vivo effects of aflatoxin B1 were studied in the chromosomes obtained from the regenerating hepatocytes of chinese hamsters. Chromatid gaps were preferentially seen in the known heterochromatic areas of the chromosome pair one, X and Y. Asynchronous divisions of the centromere were seen in both the control and treated animals, however, the frequency was 8–10 times higher in the latter.
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Srivastava, P.K., Srivastava, A.K. & Lucas, F.V. In-vivo chromoclastogenic effects of aflatoxin B1 in the hepatocytes of chinese hamsters. Genetica 45, 371–376 (1975). https://doi.org/10.1007/BF01508312
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DOI: https://doi.org/10.1007/BF01508312