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Flavin adenine dinucleotide concentration in erythrocytes with normal and deficient glucose-6-phosphate dehydrogenase

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Summary

The concentration of flavin adenine dinuclcotide (FAD) in G6PD deficient erythrocytes was approximately 1 1/2 times higher than in normal red blood cells. Probably, there is a causal relationship between the elevation of FAD and the increased activity of glutathione reductase in G6PD deficient erythrocytes.

Zusammenfassung

Die Konzentration von Flavin-Adenin-Dinucleotid (FAD) in Erythrocyten mit G6PD-Mangel war ungefähr 1 1/2mal höher als in normalen Erythrocyten. Wahrscheinlich besteht ein kausaler Zusammenhang zwischen der erhöhten Konzentration von FAD und der erhöhten Aktivität der Glutathion-Reductase in Erythrocyten mit G6PD-Mangel.

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References

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Authors and Affiliations

  1. Human Genetics Laboratory, Department of Pathology, Faculty of Medicine Chiang Mai University, Chiang Mai, Thailand

    G. Flatz

  2. The Anemia and Malnutrition Research Center of the Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

    F. Simmersbach

  3. the Departments of Pediatrics and Biochemistry, St. Louis University School of Medicine, St. Louis, Missouri, USA

    F. Simmersbach

  4. Univ.-Kinderklinik, Adenauerallee 119, D-5300, Bonn

    G. Flatz

Authors
  1. G. Flatz
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  2. F. Simmersbach
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Flatz, G., Simmersbach, F. Flavin adenine dinucleotide concentration in erythrocytes with normal and deficient glucose-6-phosphate dehydrogenase. Klin Wochenschr 48, 1071–1072 (1970). https://doi.org/10.1007/BF01497217

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  • DOI: https://doi.org/10.1007/BF01497217

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