Summary
Administration of riboflavin for eight days in a dosage of 10 mg per day resulted in an improvement of erythrocyte glutathione stability in subjects with glucose-6-phosphate dehydrogenase deficiency. In red blood cells of individuals with normal G-6-PD glutathione stability was not altered.
Zusammenfassung
Verabreichung von täglich 10 mg Riboflavin über 8 Tage führte zu einer Verbesserung der Glutathionstabilität in Erythrocyten von Personen mit Glucose-6-Phosphat-Dehydrogenase-Mangel. Die Glutathionstabilität in Erythrocyten von Stoffwechselgesunden blieb unverändert.
References
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Flatz, G.: Glutathione reductase in G-6-PD deficiency: evidence for increased binding of FAD as cause of high activity. Nature (Lond.) (in the press).
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On leave from Universitäts-Kinderklinik Bonn
Supported by Stiftung Volkswagenwerk.
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Flatz, G. Effect of riboflavin supplementation on erythrocyte glutathione stability. Klin Wochenschr 48, 764–765 (1970). https://doi.org/10.1007/BF01497140
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DOI: https://doi.org/10.1007/BF01497140