Summary
Dog kidneys were subjected to hypothermic non-pulsatile perfusion up to 72-hours and then transplanted. Human albumin was used as perfusion medium. Post-transplant function of the kidneys was measured by PAH- and inulin-clearances and by following the course of serum creatinine. Successful preservation up to 72-hours was possible.
Zusammenfassung
Hundenieren wurden zwischen 48 und 72 Std hypotherm, nicht-pulsierend perfundiert und anschließend transplantiert. Als Perfusat wurde eine Human-Albumin-Lösung verwendet. Die Funktion der Nieren wurde nach Implantation durch PAH- und Inulin-Clearance sowie den Verlauf des Serumkreatinin geprüft. Wie die Ergebnisse zeigen, eignet sich diese Methode, Nieren erfolgreich über 72 Std zu konservieren.
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Mit Unterstützung des Sonderforschungsbereichs 37 der Universität München.
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Grundmann, R., Landes, T. & Pichlmaier, H. 48–72 Std Konservierung von Hundenieren durch hypotherme, nicht-pulsierende Perfusion. Klin Wochenschr 50, 1141–1143 (1972). https://doi.org/10.1007/BF01494345
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DOI: https://doi.org/10.1007/BF01494345