Skip to main content
SpringerLink
Log in

Tierische Antisera zum Nachweis des Hepatitis-Associated-Antigen (Au/SH-Antigen)

  • Kurze Wissenschaftliche Mitteilungen
  • Published:
Klinische Wochenschrift Aims and scope Submit manuscript

Zusammenfassung

Tierische Antisera gegen Australia-Antigen, die durch Immunisierung von Kaninchen, Cynomolgen und Ziegen gewonnen wurden, zeigten in der Immunoelektrophorese und im Doppeldiffusionstest nach Ouchterlony immunologische Identität mit menschlichen Antisera. Das besonders hochtitrige Antiserum vom Kaninchen zeigte im Vergleich mit hochwertigen homologen Antisera keine Unterschiede hinsichtlich Zuverlässigkeit und Empfindlichkeit der Anzeige des Au/SH-Antigens bei der Untersuchung von 220 Hepatitissera.

Summary

Antiscra against Australia antigen obtained by immunization of rabbits, cynomolgs and goats are showing immunological identity with human antisera in immuno-electrophoresis and Ouchterlony's double diffusion test. The study of 220 sera from hepatitis patients indicated, — especially when rabbit antiserum was used — the presence of the Au/SH antigen of a reliability and sensitivity equal to those of high quality human antisera.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Alter, H. J., Blumberg, B. S.: Further studies on a “new” human isoprecipitin system (Australia antigen). Blood27 (3), 297–309 (1966).

    Google Scholar 

  2. Becker, W., Bonacker, L., Schwick, H. G.: Ein einfacher immunologischer Schnelltest zum Nachweis des Au/SH-Antigens. Klin. Wschr.14, 887–888 (1970).

    Google Scholar 

  3. Committee on plasma and plasma substitutes: Statement on laboratory screening tests for identifying carriers of viral hepatitis in blood-banking and transfusion services. Transfusion (Philad.)10 (6), 1–2 (1970).

  4. Gocke, D. J., Howe, C.: Rapid detection of Australia antigen by counterimmunoelectrophoresis. J. Immunol.104, (4), 1031–1032 (1970).

    Google Scholar 

  5. Lichter, E. A.: Chimpanzee antibodies to Australia antigen. Nature (Lond.)224, 810–811 (1969).

    Google Scholar 

  6. Melartin, L., Blumberg, B. S.: Production of antibody against “Australia antigen” in rabbits. Nature (Lond.)210, 1340–1341 (1966).

    Google Scholar 

  7. Pesendorfer, F., Krassnitzky, O., Wewalka, F.: Immunoelektrophoretischer Nachweis von „Hepatitis-associated-antigen“ (Au/SH-Antigen). Klin. Wschr.48, 58–59 (1970).

    Google Scholar 

  8. Saravis, C. A., Bonacker, L.: Membrane-complement fixation test for hepatitis associated antigen. Nature (Lond.) im Druck.

  9. Schwick, H. G., Störiko, K., Becker, W.: Qualitative determination of plasma proteins by immunoprecipitation. Laboratory Notes for Medical Diagnosis, No. 3, May 1969 ([Behringwerke AG, Marburg (Lahn)].

Download references

Author information

Authors and Affiliations

  1. Behringwerke AG, Marburg a. d. Lahn

    L. Bonacker, W. Becker, K. Störiko & H. G. Schwick

Authors
  1. L. Bonacker
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. Becker
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Störiko
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. G. Schwick
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bonacker, L., Becker, W., Störiko, K. et al. Tierische Antisera zum Nachweis des Hepatitis-Associated-Antigen (Au/SH-Antigen). Klin Wochenschr 48, 1423–1424 (1970). https://doi.org/10.1007/BF01488818

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01488818

Search

Navigation