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Lactatbildung aus Zuckern und Zuckeralkoholen in Erythrocyten

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Zusammenfassung

Erythrocyten können Lactat bilden aus Glucose, Fructose, Sorbit, Xylit und Ribit. Mannit wird nicht umgesetzt. Die Kombinationen Xylit + Glucose, Xylit + Fructose und Sorbit + Glucose ergeben additive Lactatbildung. Bei den Kombinationen Xylit + Sorbit, Xylit + Ribit und Glucose + Fructose addiert sich die Lactatbildung nicht.

Über Konsequenzen dieser Befunde für die parenterale Therapie wird diskutiert.

Summary

There is a production of lactic acid in erythrocytes from glucose, fructose, sorbitol, xylitol, and ribitol. Mannitol has no effect. Combinations of xylitol + glucose, xylitol + fructose, and sorbitol + glucose lead to an additive formation of lactic acid, whereas combinations of xylitol + sorbitol, xylitol + ribitol, and glucose + fructose have no additive effects. On the bearing of these data for the problem of parenteral energy supply is discussed.

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Literatur

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Authors and Affiliations

  1. Aus dem Physiologisch-Chemischen Institut der Johannes Gutenberg-Universität Mainz, Germany

    K. H. Bässler & W. V. Reimold

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  1. K. H. Bässler
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  2. W. V. Reimold
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Bässler, K.H., Reimold, W.V. Lactatbildung aus Zuckern und Zuckeralkoholen in Erythrocyten. Klin Wochenschr 43, 169–171 (1965). https://doi.org/10.1007/BF01484510

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  • DOI: https://doi.org/10.1007/BF01484510

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