Zusammenfassung
Es wurde der DNS-Gehalt im Plasma fünf gesunder Testpersonen ermittelt. Elektronenmikroskopisch darstellbare Strukturen konnten als doppelsträngige DNS charakterisiert werden. Bedingt durch die Isolierungsmethode resultiert die gefundene DNS sowohl von freier und/oder DNS, die in komplexierter Form im Plasma vorliegt. Die Moleküllängen variieren von weniger als 0,2 µm bis zu ca. 13 µm. Die Konzentration liegt im Bereich von 3–11 ng DNS/ml.
Summary
The DNA content in plasma of five healthy human individuals has been estimated. Structures ascertained by electron microscopy have been identified as double-stranded DNA. Depending on the isolation procedure applied the DNA molecules found may originate from free and/or complexed forms of DNA. The lengths range from less than 0.2 µm up to about 13 µm. DNA concentration is in the range of 3 to 11 ng/ml.
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Dennin, R.H. DNA of free and complexed origin in human plasma: Concentration and length distribution. Klin Wochenschr 57, 451–456 (1979). https://doi.org/10.1007/BF01477498
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DOI: https://doi.org/10.1007/BF01477498