Comparative investigation on the influence of human bovine collagen types I, II and III on the aggregation of human platelets

Vergleichende Untersuchung über den Einfluß der Kollagentypen I, II und III von Mensch und Kalb auf die Aggregation menschlicher Thrombocyten

Zusammenfassung

Die Kollagentypen I, II and III von Mensch und Kalb weisen in löslicher und strukturierter Form deutliche Unterschiede in ihrer Wirkung auf die Aggregation menschlicher Thrombocyten auf.

Eine besonders stark aggregierende Wirkung wurde für das Typ III Kollagen gefunden. Die pathogenetische Bedeutung dieses Befundes wird kurz diskutiert.

Summary

Collagen types I, II and III from man and calf are distinctly different with respect to their effect on the induction of the aggregation of human platelets. Collagen type III was found to be a particularly potent inducer of platelet aggregation. The pathogenetic implications of these observations are briefly discussed.

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These investigations were supported in part by SFB 51.

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Balleisen, L., Gay, S., Marx, R. et al. Comparative investigation on the influence of human bovine collagen types I, II and III on the aggregation of human platelets. Klin Wochenschr 53, 903–905 (1975). https://doi.org/10.1007/BF01468982

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Schlüsselwörter

  • Kollagentypen
  • Plättchenaggregation

Key words

  • Collagen types
  • platelet aggregation