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The morphological and clinical course of the different forms of glomerulonephritis

Morphologischer und klinischer Verlauf der einzelnen Glomerulonephritisformen

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Zusammenfassung

Der klinische und morphologische Verlauf der einzelnen Glomerulonephritisformen werden anhand von Mehrfachpunktaten der Nieren von 291 Patienten miteinander verglichen. Dabei ergibt sich folgendes:

  1. 1.

    Jede Glomerulonephritisform hat im Sinne der Wahrscheinlichkeit eine eigene Prognose, die nur wenig durch medikamentöse Therapie beeinflußbar ist.

  2. 2.

    Die Prognose verschlechtert sich erheblich, wenn ein Hypertonus oder tubuläre Läsionen im Sinne eines akuten Nierenversagens hinzutreten.

Summary

From repeat biopsies of 291 patients with glomerulonephritis, the clinical and morphological course of the individual forms of glomerulonephritis were compared with one another. From these results we concluded that:

  1. 1.

    Every form of glomerulonephritis has in all probability its individual course and prognosis, which can only be very slightly influenced by therapy.

  2. 2.

    The prognosis is considerably worsened, when either hypertension develops or tubular lesions in the morphological sense of an acute renal failure.

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Authors and Affiliations

  1. Pathological Institute of Tübingen and the Departments of Internal Medicine of München, Bonn, Freiburg, Augsburg, Heesen and Göttingen

    H. Fischbach, A. Bohle, D. Meyer, H. H. Edel, U. Frotscher, R. Kluthe, D. Renner, K. Rinsche & F. Scheler

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  1. H. Fischbach
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  2. A. Bohle
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  3. D. Meyer
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Dedicated to Prof. Dr. Dr. h.c. Dr. h.c. E. Letterer on his 80th birthday.

Supported by the Deutsche Forschungsgemeinschaft.

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Fischbach, H., Bohle, A., Meyer, D. et al. The morphological and clinical course of the different forms of glomerulonephritis. Klin Wochenschr 54, 105–116 (1976). https://doi.org/10.1007/BF01468787

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