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Über das Verhalten des Histamins im Plasma und im Magensekret bei Patienten mit perniciöser Anämie

Concentrations of histamine in plasma and gastric juice in patients with pernicious anaemia

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Summary

In patients with pernicious anaemia (n=10) the histamine concentrations in basal and maximal stimulated gastric juice showed significantly decreased values when compared with those of normal individuals (p<0.0005); the plasma histamine concentrations, however, were significantly increased (p<0.0005). A possible parallelism between the increase of plasma histamine concentrations and the relatively high levels of serum gastrin is discussed.

Zusammenfassung

Bei Patienten mit perniciöser Anämie (n=10) waren die Histaminkonzentrationen im basalen und maximal stimulierten Magensekret gegenüber dem Normalkollektiv signifikant erniedrigt (<0.0005), die Plasmahistaminkonzentrationen dagegen signifikant erhöht (p<0.0005).

Ein Zusammenhang zwischen den hohen Plasmahistaminkonzentrationen und dem in gleicher Situation erhöhten Serum-Gastrin wird vermutet und diskutiert.

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  1. Gastroenterologische Abteilung der Medizinischen Klinik und Poliklinik im Klinikum Westend der Freien Universität Berlin, Germany

    D. Stopik

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Stopik, D. Über das Verhalten des Histamins im Plasma und im Magensekret bei Patienten mit perniciöser Anämie. Klin Wochenschr 52, 990–992 (1974). https://doi.org/10.1007/BF01468660

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  • DOI: https://doi.org/10.1007/BF01468660

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